>rIIB_RB16 membrane-assoc.; affects host membrane ATPase
MRTVKILDDVQKKAVYEGFLTSANKTALAKQFGVSVRTIGRVITEQHAKYAHEEQKPLPK
TDTGSKMIGSESFITLVRNGEIITADSNHPNFEKAHVLLTKGDIEGVAALLNTKQALKVF
SKGNIKIIGHKVMYKDVVFDSGITQRIVREMYNERPYEHLVNFFEKLMQNPSRDAVYQLY
GFLVHNDIELADDGDFYAWKRVSEDYKDMATGKFDNSPGAIVKMPRNQVDEDKHKTCSCG
LHVAAKSYLPHYGGGRGRVIQVKVNPRDVVAIPVDYDNAKMRVCRYQVMTDVTAGFSHY
>rIIA_RB16 membrane-assoc.; affects host membrane ATPase
MKLRESQASTVHRVGIESGSRRAFGMRAGKKAFKILSSTIYKYKIRAIIREISCNAIDGH
IVAGNMDRFDVQLPTVLDPRFIVRDYGTGLSDYMVNEVFTVYFESTKTDTDDLIGALGLG
SKSPFCYTSTFTVESIQDGMKRGYTAYLNEDGEPYIDPLYAVETDEPNGVQVTVPVNVED
IPEWEREAARVYEAFTTIRPRFIGVQLDINWQPTEANNRGIIRYKSKHYSGLFARMGNIC
YPIDLDMFRDSLFYCYQNSDYAYILDFPLGTLDFMPSREELSLDKITKQAILDRLKGINE
CYYSELTEDFAKLKTTREKVIWYQNLPTMLQSFVTRDKKFRVGNITLSDLVMHFNSKDLI
TNMQIWGYWANTYDGKDCSFERTGSGCRWVTFKSETMRRQDITRMLHPWKQRNLYLLQND
NNAKSVRAYAIGYCMLHKTDRMNFVEYDPNRNQDNLQNFIKNGYYDESEIVYLKTSEMTE
ELEVYTEDRRRWRATRETIDKDSEPRPKTPTAYRYTVGINGDLNKEDLFLTKAEFVNLES
AYALRLYGVDDYSSLSESNNFSMSSIMNNLATVMEISGVRVVYTLRNSLWNKIPDSRMIC
LDTFLAELFCKTAKEMKPNWYPAFVSKKYRGSVKELYENLGISLDRMVKNRYDSRRYNIL
NTLDGKVLMQTTEDGETTEAKNPSIRVAQARHEEMEHAMIERVDEQYEIFAKRNPLIARI
LRNSDGYQIRYILEDKAMTDDMVKLIRWK
>RB16ORF002c hypothetical protein
MRPCSAPNTSKYVAIVILSTIAMCFVTAIVFGILEMKKDEKRKQEIYDYMDRMCTPLEYG
IDKKPTKYSCENIIFNK
>RB16ORF003c hypothetical protein
MFKTRSDMEITIWAKSIMAKHGLSHWSFKINGRFKRTLGCCSYSKREIQLRRKHVEEDTY
DCILDTLMHEIAHALVGYGAGHGPVWQRKAIELGAKPTSSKVRVREKEIIEKKDDHVYAM
FLKTSNGEVYQSTMPEKMYNEIQSGKRNISTMYMVGHKASTKGRLVARKLTSQEFAKVLQ
>52_RB16 DNA topoisomerase sub; membrane-assoc.
MERSIKDVVQVEGLTFALYTIYSRAIPHLVDGFKPVHRFFIHSAAKGGTGFQKVASIAGG
VAMYGYHHGETSVEEALSLMAAHWCNNIPLFERDGFFGSRLVKKPGAPRYIKCKLSPLFK
AIYMDEDLTLPHEDPEHVPPAYYLPIIPMVLVNGFSGIAKAYATNIPPHDPVSVLNGCVS
YLNGKDFTLDLKYPHFKGDIENGTMYGKYELQGKTKLVITEIPVKYDRVKYISILDKLEE
KGYIVSYKDLSKEDFRYEITLKREYANGLTREKILKDFGLIENSNPNINVIFNGKLHSYE
RPETLLKDFVDIRIGVYQQRIDKRIQETKEALDKALAKVDFIDQMIAQPDALKGLSRSEA
VKLVSTWAGCENHAEILVAMNIYHLTTDERQKLEDEANELRKQLKYWEETTPKTEYLNDL
KELSKKLK
>60plus39_RB16 DNA topoisomerase sub.; DNAdep. ATPase; memb-assoc
MSLDFLMDEEEPQKVPETPKGVEVDESFCLSDRDHIRKRPNMYVGSVNREAHERFIQGKF
RKVEYVEGLVKIINEILDNSIDEAIRTDFKFANKIEVKIDHNLVTISDNGRGIPQDDVRT
PEGKIVPKPVAAWTMAKSGSNFDDENRVTMGMNGVGSFLTNCYSSIFIGETSNGKRKVTI
NCTDGAQNMDYRTSPTKEQGTTVKFTPDFSIFGVDGIDEETKEVIKDRLMALAVAFPSVK
FTYNNEVLPNKFAMYGAMYGEKTIVQTNNKISFILASTEDGFKQKSFVNGLDTKNGGVHV
DCMIDGIYTELEPMIKKKHAIEIPKARVKECLTLVVFLHNFNAPAFDSQTKEKLTNTAGE
FNNHAGLNYKKIAKQIMDTSEIITPIIESALIRKQAAEAAAITKAKKKAKKAKVAKHVPA
SGIDTDGVETTLFLTEGDSAVGQFIECRNEETQGAFPLRGKPLNTWGMSNSDILKNKELF
ELMAILNLHPGDSSEMTYDNIGIMVDADVDGGDILTLLIAFFSRWPELFAKKKIRYIRTP
IIIAKVGREEKWFYSLDDFTPFRDKAKEARYIKGLGSLRKEDYDRVLGDQLKYDTIVLGD
EYKDVLELCFGDDSDPRKDWVNGKHRFSRVD
>RB16ORF006c hypothetical protein
MSKINETIPDDYGYADGFQPQEYCDKLIVEFDSESVSQITRINQYGFEIALTRMQVEELI
PILQKIKDA
>39.2_RB16 unknown funct.
MPTYTYKCKKCEKEFPKMSSIATRDAPKDCECGGEAHRTVDKPQMVKGGFPYV
>motB.2_RB16 unknown funct.
MLVYRVELNVSVIRDQNCGKTQWTRNIGPYVTQVINNKTLKWLEQFYINPRPCVSIDDDR
HPAPWEDLRLSRSLNGGGFDGFHFGFASLPKLSKWFNKYERERLHNCGFVCMVYEVDRLY
AGKSQCVFDMRRANLIDMLSLKEIY
>RB16ORF009c hypothetical protein
MSKYKVGDMYAPKSIFLAVVQTCKPTDPVRRIYEALRKNPMDFNAPRKISIVMLNSVYLE
GIPCPVTFDTLKTLFNPVYIATREEAEATRNDVVVPELFRKILEEANAGGEVAPRESTSV
VLDDFFKVAHRVKKRHKSDVVHHMAAEVGEVSECIIQPQRGGNIVEESVDVILCALDVIN
LELNATHGTHEIAQVVNKLVAKKLQKWYDTCS
>RB16ORF010c hypothetical protein
MSRPKNSKTNVVLCYDDKPGKPCSNAKFMHIAGLPGMVKRTSYDSHYNEETTCVYLDDVL
MAERIMQCVHFPGERPTVNCFIFGYYKGIVNEQV
>RB16ORF011c hypothetical protein
MKLSGTARFAIFGLIAAGVFFFAWQSRDPNKAVYQAAEHAAEQDSIAQHEKMLQERRDHG
FVETVNYTNAFGDVTERVVNVLGRTKGTTFTITREGSGKLASACFSAITDDEKRNLFAPY
FYTKVYAKFDGGETKEFSASRGATDDYLCISSPQRFLFNMDRATVMQVQLIFLDHYSKVP
EVHEWNLKTYNEVVNK
>RB16ORF012c hypothetical protein
MNTFETLANAAAPYLNAMFVARNARFQDSPFETVFTLEKGRKYHRIVQDTRNKETGGMFN
QRSVAGFLDNDGNIYKAAGWKAPAKGIRGNIFNNPENSIDSSGYVKYLR
>RB16ORF013c hypothetical protein
MVNGSLHQQAVKQWTQMVQDAERGIAYCDEALASNLEPWERKEYEKVKQNHIAELPALKA
HLNYLLENQ
>RB16ORF014c hypothetical protein
MYNVTKVSIKDITVGDTVIYQGNMRTVGKNDIKRDPLFGVLLFGDSHNLARTLIERVTFP
KWYQGKLVS
>RB16ORF015c hypothetical protein
MENLKAKVVKVLVKNGFNEENAVVMVEKNLADALKIRPEAKPAKLAEVIVCIM
>RB16ORF017c hypothetical protein
MNTIILIGLILISVGGAFVIHSLYRHGEAHDWFKYNTRQFVKHFRGEGVTTHVNLYEGFV
EFYFTGHGESHTLKKTIVEAKAIYDQTRDGGIRKRLLR
>RB16ORF018c hypothetical protein
MRIAVLGGTMISRTLVSCLIDSIRWVRTPCVDLCSRIPYDEPTVYKMKPYQIPLINRALH
RQSVNRGK
>RB16ORF019c hypothetical protein
MFDLKEGFKVVFVFAIIGMISVVSIGLWLSYEAIVWLGEWLRILATR
>dexA_RB16 Exonuc. A
MSHLPVDYVWDYETVGPSPNGKLVELSYVPFIDDPHNPPTFAELVSRGRKYKFDLKKQPD
RIADKSTIDWWKQQSEEARAILKPSPDDIDLYEGHKQFFEDLKADGVSRWQSLDYVRGPE
FDRGILVDVVRTMTGKVDIFDDMPTVFWNSRDVRTAIENRLLTRGASTCPLRKGILNGFV
MHNSIHDCAKDALMLIYAMRYAMGLEEPPTEEETDELSLPRKR
>RB16ORF022c hypothetical protein
MKTDISMKFPRLHADLIADLILKTPREQIPLHVDYDYLCEFVEAVENTKRLEQSIYNCGL
RQFGMQMLSNEEISEFDITPRVALALAGFMEEYKRIRNVTSSS
>RB16ORF023c hypothetical protein
MKLSINVTDIQQILNAVEKIREKDPHANSMFAMYSTIDPADVIRKLKYIDSYNKNLYCPN
GPSYSWGNVALTVELTYEEYGVVTMILRVMRNLRENKDLWYLP
>dda_RB16 DNA helicase; DNA-dep. ATPase
MNELTFDDLSDDQKAGHDRVIKNIQNKVHTTITGGPGVGKTTLVKFIFETLKAMGISGLW
LTAPTHQAKNVLAQATGMDATTVHSALKISPVTNEEIRVFEQQRGKKAADLSECRVFVVE
EVSMIDTELFRIIKRTIPSHAVILGLGDKDQIRPVNSDGKTELSPFFDEEIFDVIRLDKI
MRQAEGNPIIQVSRAVRDGKMLKPMSVGDIGVFQHANAVDFLKQYFRRVKTPDDLIENRM
FAYTNDNVDKLNATIRKHLYKTTQPFIVDEVIVMQEPLVQEMRLNGQIFTEIIYNNNEQI
RVLEIVPRTEVIKADKCDEKISIDYYLLKTVSLEEGTNAQIQVVVDPVMKERLGNYLAYV
ASNYKRIKQQTGYKAPWHSFWAIKNKFQDVKPLPVCTYHKGQGSTYDHSYMYTRDAYAFA
DYDLCKQLIYVGITRARFTVDYV
>RB16ORF025c hypothetical protein
MIAKYYIIVTKDKDGFTVPYTEKGKPPELFLTQDAAASKLRFIQSCFEQKINYVPEEPRF
SFFRKTEQLPATEEQKKEMRWFIENSKIQGVILKV
>56_RB16 dCTPase; dUTPase; dCDPase; dUDPase, essential
MTDKTPVFNSCAHLVNPADLEFVDNEYKKVLARNGDPLQSMLDLQNHAQQSLSDTLSWVP
RPDGLKTCGEILDWLKLQDDAIEDETRELYTALGGMSRGAKAASGVWKPWKSNHQALRNQ
VFAEMKEEDKLEILFELIDQWHFFMCKFLALGLDAETIYKLYALKQAENLRRWANNY
>61_RB16 Primase, req. gp41 for priming at uniq seq
MYLDIEFATRIMGSLPQSEIVRRGGSLSIHSRCPICGDSMKDKHKKRFWIYPSKKGDHMN
CGCFNCGYNRPFTVFLKDYYPDDYRDYLMESFKDRKQTKQTHVEPPKEEKKYIPELQFCE
RLDTLPESHPIIKYVAGRHIPKDKYDRLWFTRQWQHLVNSITPDAYPLPKDEPRLVIPIF
DNKGKIESFQGRALRDNAAAKYMTIKACEQSTKIYGQDTIDPLKTVYFLEGPLDSLFVDN
AGAITGGQLALSEVPYKNMRVWVLDNEARHPDTCSRLLKLIESGEKVVMWDKCPWPSKDI
NEMIKEDGATKAGIMQYLKDNTVHGLTAKLRFKAWDKSPKK
>RB16p027nc_RB16 not conserved in RB43 ; hypothetical protein
MKPFPPLNYRIWVTANNYTWFPIRIRYMSDTVVVYTNVRKGTSGVDIPRSRSFNDVFCDW
KITLDGTENEVYE
>61.1_RB16 unknown funct.
MSDQLVKNMDLTYSVRMIRLLKKPFTEWTAYKLGIIDGQGEVLKNPKTKEEQEAYSPFHR
SVRHIKRRLNAVPYMSGFMNLTSMYDSLRNRYNLTEEDHEMIMMNMPEMRQIMNEEMVAG
DSGGSVENIASGVTTGAITNKGPKVLGSTRPHKRKRKIMKSEE
>RB16ORF030c hypothetical protein
MESDKALTYDEKLFIIENFHEGAFTNNSELGAFFTPIGLARDFTIDACTSGSVVDLCAGI
GGLSFAMLHMMMYAKPREIVCVELNHTYYKLGKRIVPEATWINADALTTEFDTLFDMAIS
NPPFGKIKTSDFKGKYTGAEFEYKVIERASQIARMGTFILPQMSANFRYSGERYFRQDES
TTSSKCKKFLDETGLEMQPGCGIDTGYYLEDWKGVKPLCEIVCMEFPEPETKPAQNLFTF
TIE
>RB16ORF031c hypothetical protein
MSDLLHDILVAAYPDDEEPKFDSPYRSEWIVSVDDKGYVDIMRWPNIHPGYLDEGINAEM
LGMPEQVEDPAGVYKWICSPWETRDWESNIVDDWGFDVVESTPLFLLPEKVNGEVNESGN
QTTQQDNGSGGV
>RB16ORF032c hypothetical protein
MKLAIAFILLVLNALMGFPFPWLVLLAIPFAWNLFRIGLAGCVGVLMLIIGAIGGKDAFI
GVLKAMKEGVKEGLVK
>RB16ORF033c hypothetical protein
MNLLNNPYDEVLNPELNFSSGYFDAVVNSVVNRGLLVEMLKGAKADVEGSVEFLWNFLPI
DPDFKVGCNEEQAKNVLRYLINKA
>RB16ORF034c hypothetical protein
MKILSVVFLILLGLKLAQVGLMATASWWWVFSPLILLTVGKIAVWVVITVAVVGVFPAFS
RWVVKSTR
>41_RB16 Rep. and recomb. DNA helicase; NTPase, essential
MIVETIFSNLVFNGTYFVQAWPHLKRDYFEGNAQVLYDLMDKHVQEFNSIPSQTALEVAL
EKRSLSDVVYEDTKKMIRSMKNAPEDLDWLMKETETYCKDKAMYRALSRAIEIQANAEKP
AGERNNKIPDVGAIPDIMAEALAISFDSSVGHDYFEDYEKRWMLYQSKAMKIPFNIPILN
AITKGGAERGTLNILMAGVNVGKSLGLCSLAADYLQSGKNVLYISMEMAEHVCSKRIDAN
LLDVSLDDIDNGNITYADYKNRMERLKQTKVGRLIVKQYPTAGANANHFKALIKELKLKK
NFVPDVIIIDYLGICASTRVRGAENTYILVKAIAEELRGLAVETNTVMWTGAQTTRAAWD
ASDISMGDVAESAGLPATADFMLAVIETDELADQGLQVFKQIKSRYGDKNHFNHFKLEVR
KGNQRWMDTDNSDIGFKSDYKGRQMPKTVEEAQGAMVKQAEGNRSKLAEAAKSMNIEF
>40_RB16 membrane-assoc. init. of head vertex
MDIEQKTQNILDEAMQDVIQELLINDENDVAHLVYIHKVYWDNGLKVEFSTPDENKEALI
PLVHDAIYAQIAPNLPKPEKTLWAALKVKLYNFFQMFANLV
>uvsX_RB16 RecA-like recomb. pro; DNA-ATPase
MSNKALLKKLIKNSNSQSASILSESDVFNNITKTRTRVPILNLVLSGAFDGGLTSGLTLI
AGPSKHFKSNLGLVAVAAYLKANEDAVCLFYDSEKGVTKSYLKSMGVDPDRVVYTRITTV
EQLRNDVVSQLDALERGDKVIIFVDSVGNTASKKELKDALEDNDKQDMTRAKALKGMFRM
VTPYLADIDIPMVCICHTYDTQEMYSKKVISGGTGLMYSADTAIILGKQQVKEGTEVVGY
DFIMNVEKSRFVKEKSKFPLHVTYEGGISMFSGLLDLAMEMNFVQTPTKGWRGRAFLNTE
TGELELEEKKWREAETNCIEFWKPLFKHQPFIDAIQDKYRIPDKEITDGAALEDLYSDDV
VESNKVDFDDDIPDDVDLMEE
>43_RB16 DNA polymerase; 3' - 5' exonuc.
MTEFYLSVEQMGDHIYERFIDSEGREQVRKTKYEPTMYQHAMAGVDSPYKDIYGKTCIKK
KFDSIKDAKSWMQRMKDVGMEALGMDDYRLAYISDTYRTEIDYNRERIRIASLDIEVTAP
EFPDPREAKYAIDAITHYDSVEDKFFVYDLVEGGLDEWVASKVDTENEISEEDLKKVVYR
SFSTEKSLLSAYIKDWKERTPVIVTGWNSNKFDIAYIITRYLNIFGQNVVRHFSPFGKVT
AKTTTDQYGNEQLGYEIYGVSQMDGMDLYKKFSFTPQPSYGLGAIAEYETGKSKVDYEGS
LSELRQADHQKYITYNIVDVIRVLDIDGKRNFIELVLSVAYYAKINFPGVMSPLKTWDAI
IYNSLREDKIVIPENKRHTKTPYDGAYVKDPVVAPYKYIVSFDLTSLYPSIIRQVNISPE
TIANSFAVRPMHEYINKTAPRPSDEFSCSPNGWMFRRDVKGVIPVEIKKVFDQRKMWKKR
MMAGERNLELIKHELEHLTDAHNQMIDPDFDFYTDFSDESKAVLKTLTKQMLKAVKKVCE
KKIAQANTAQLNRKISINSLYGALGNEHFRYFDIRNASAITMFGQLAIQWIERKVNEYLN
QLCNTTDYAYVRYCDTDSIYVCMDNVIEKVGGESKFRDNNHWVDFLDKFSRERMEPIIDK
GYRELCEYMNNVEHLMFMDREIISGPPLGSKGLGSFWTAKKRYAANVWDSEGTRYEKPKL
KIMGMETQRSSTPTAVKKFLKEAIRRILQEGEESLHESFKVFEEEYKALDYREIAGVSSA
NNITKYNDGMGYPIKGTPNHIKGVLFFNRHTKGIPGVTQIMEGEKVMVLPLRDKNPWQAD
CIAWQSGSRLPVEIESDILKWVDYNGLFEKHVISPLQNITEACKIDYEKRASLNTLFGDD
W
>RB16ORF039c hypothetical protein
MKISIEEILKSLKTDDHLIIRLHRDEIDLSLTCNLSDLRTYNYAQNYFPNFYKRIMNEYT
LLVNQLNSIEGHKTLRDSAQRSLDLIKLAGVSFLIRLNAEKEKRND
>regA_RB16 Translat. repressor of early genes
MNMLEIKLSSDDSFLKIRETLTRIGIANNKKKMLWQSCHILQKQGRYFIVHFKELLRLDG
RQVDMTEDDELRRNNIARLLEEWGMIEILTPDLKFSEENNFRVLTHAQKAEWTLKYKYRI
GH
>62_RB16 Clamp-loader sub, essential
MSLAAFLDEEELNEHEAAWRSKDWDKIEGLVKEYTKDKENTLFMVLEELNTGKKPLRISG
LDSYDKYFIDNAMSQHIETLIPAYTMNMIGSGLPDQAHFDYYLHTVRKGKRFGAWAKLTE
DNEIKVILHVLQKRYGVNTRIAMEYYEELKQLEKLDEWKRKNMKVAISVLADVVKNKTDQ
KKVEQLIKKW
>44_RB16 Clamp-loader sub, essential
MELSENVQLIDTKYGKISQSPDEFAWDQRYRPTTIDECILPAADKETMRGFIKSGRIDNM
TLVSDSPGTGKTTLALVLGNEVDAEVMFVNGSDCGVNFIRNEMDRFASSMTQKKGGKIIL
IDEFDRPGMAEAQKHMRSFIEAYSKNVTVIVTANNINGIHPALLSRCPPVKFGSPSKEER
IELMKQMIKRCFGILEIEGIEYDQQVIAAFVKKHYPDARSIVKALGFYSKRGKIDAGILS
EIVGSDITPVIEGLKAKNFKALRAEAIKYAPEYETFLSKLLDAIYPIVTNESKVALIQAI
GENNAQYGLAVNKEIHLQYLFMGLMLTLAWEA
>45_RB16 sliding clamp DNA pol; enhance late prom, essential
MKFSKQTIDILKNFSQINPSIMLTKGSFIMTKTINSVVYAEAEIPDVIDEDVGIYDLNSF
LSMLNIVGADAEVTHDLSTGEIIIRGDKMKIVDRSCDPTTIVKPKKRLQMPVADLVFQIS
ASDFEKLIKASRMMKLTDLSVEPINGKLVITAKSKESQSTFSVEVGDYEGDNVFNFDMKI
DNMQFINSDYKVEISAQGAAKFSSENGVAYVVVLEATSQFK
>rpbA_RB16 RNA pol binding
MNLEQNVYVAHLNNVRKSWVSKTPDNIKEMFRAMPQAERFEHYKRIDEAVIEVREKVVAD
AHNSGKKLNDAEHKKIFDTAAQIVVNSLINGTFA
>32_RB16 ssDNA binding, DNA repair, rec. and pre-synth.
MSFFKRQDPTKLQEQVAALKGSSGFQKDEKEWKLTLDAQKNGSAVIRFLPNRSDDELAFV
RIVSHSFKKQNQWYIENCPSTHGDYDGCPVCQYISDNDLFEKAKANKGGEADKLLGQIGR
KQSFWANILVIKDPGAPENEGKVFKFRFGKKIMDKITATIAGNPDLDEPGIAVTCPFGGA
NFTLKAKKVGEWPNYDDSTFGVPGPIKGIDEEAVQKAIFEGMSDLRPITAPDQFKPAAEL
TARFTKVFGGGAALGAGASAGADLDSELNSFDNDLKNFDNSNQSKGAKESGGVSQLNVGG
SVPEDDTPPFDLNEGSGDDDLDKLLDL
>59_RB16 Loader of gene 41 DNA helicase, ssDNA binding
MKFKTPFGSSDANSRLKPIAVYKLYLVMKNHFAGRYDAIKYKWEIKITEQAFQKRKDRYF
FTKLAERFTFKEIYLILLCNMVANPDFWVGDIDEDTIVFYRQYIGKLRRIDNIFVDDVKN
LYEFSRMKGIPLSTVFQYSVKSSTSYISKLVQSGVISYESFLILDSFLDIINKHDEIATD
FVWNEFSKKLNAYRKLVEISDEEIVKYRNLMKQTLTKLNEK
>33_RB16 binds gp45 and gp55, late prom transc., essential
MSEIGNKTEVGLYIENLVASEGATYMEATLQWMDENSIDYSMLNKTVPKAIIDKISDEAI
KNNLLRPSVAKDHTTTQTLDDFM
>dsbA_RB16 dsDNA binding
MSIELLQENPEIAKAIKDMIKEASNVKTQIEIHQGTLKDIKSKAKTDYGIDGKTFSKLFN
LYHNQARTEFEEQNNELIELYDVIDKA
>rnh_RB16 RNaseH; 5'-3' DNase; yeast FEN homologue
MSSFASMFNLNSLMSNEDDPVDVMCIDISNLSVATLMNNFKPKDQKDINQQIIRHIVLDT
IRYNVVKFKGEYPEIVLAFDDNKYWRRSKAWYYKKKRQMEHAESEWDWDFLNGFLHPTYD
EIRENLPYKGLRVDFAEADDIIGVVTKNAVAQGKRVLIVSADSDFTALQKYQGVRQWSPT
QKKWVTPKYGTPRNDLRMKIIKGDKKDSIACIKMRNDYIVTKVEGERAPQIRANELELWL
DADDPTVHMTPEWAARYRENEELRDFDFIPKDVADEIEKAYNNPKSGNKAKMEKYFMENK
LVRMFEKLSDF
>55_RB16 sigma factor recog. late T4 promoters, essential
MTTKIYADNDKLYPVMCKWKQQIRETGDRKMPDDLGIAIMNIAHGLARRYNFNRYSEDWK
MDMIDDGISATISGLHNFDETKYTNVYGYINKACWQAFVTRILYEKKENAKKYKYFLEHV
YDSDDADMTSIADETFIQDIHDKLNQYEESAKKPKDKIEVVDESPTLEMFL
>a-gt.5_RB16 conserved hypothetical protein
MKIKIDLNKILADAENEIDLLPYLVKLELQNVGVPVIIDPTDVRDPDFAIESGRLDYVIN
AETMIMEITYYDRAA
>a-gt.4_RB16 unknown funct.
MTEQHEVLDEVAHEKTATELREEELESLKGTRVEQEALSKAQKYMRKNRAEWKRLHKHAE
NALFDGNKAQYVYAIKKMRDMLKQPYNDELIETMWITSNQQLKDLFVMASEKYGK
>47_RB16 recomb. and nuc. sub
MNYVLIGDTHAGLRQDNPWNEDNLYEVFKQIVAYCKEHGITRGFHAGDFFDVRKATTQTT
MNFVREKLVPLLTEAGIVIDTLVGNHDCQFKDKIRPNAPREILSQYECFNVIDEPTTVDL
GGGKSIDLIPWICQENSHRIFEFIKQSKSNFCLGHFELSGYYFYKNSKADHGLEPDFLKK
YERVYSGHYHHANEGDNVFYIGTPLTMSANDEDETRGFYVFTGTPELTFIANPVCHHRRI
SYPAQKDVDLEQFRNCAVRLIVSEVDSNLAKFQTKIEEIAYEISIIDNVKTDSDVDTDFE
IKTVRGLMGEYVANMQITDDEKEDVNRMISELYAEVSGA
>RB16ORF054w hypothetical protein
MHSRYEKYFGENPRYSHLLRMLGMKHIIATSDEAGETSAVCLTIMKGAWHSSRTWSIFML
DTLDDDTLSYTIDSSVVQLITELCERILNETKN
>RB16p054nc_RB16 hypothetical protein, mobile element not conserved in RB43
MKLKTKSHGGGNRTIDDEISSINELLPMLDVDVVLGKIYWKNSPRKSVPAGTEAGSKTKH
GYVAIGYKKTYYRRHRIIFYVANGYLPLVVDHKHGVESGDGIDNLQDITQQQNSVKMRMS
RRNSSGFRGVSFHQKSGKWQSCIVYNRKTIYLGLYETPELAHSAYTDKRKELFGEI
>46_RB16 recomb. and nuc. sub
MKLNFRKIKYQNILSVGNTPIELEFDTAKKTLITGKNGGGKSTLIEALTYALFGKSFRDL
KVGQLVNSVNKKKCLVELDIEYGKDSYKVVRGQKPKVFEIWKNGDKLAEDSAAGDYQSQL
ESMLNINLVGFKQVIVLGTAGYTPFMELKTPDRRKLVEDLLSLSVISEMDKLNKSYVRGV
NQQLDTLSMQVNHIQQQIATHQRFIDEQRAKANQNNARYKEIYDSHVETAKNIKAQLMQL
QAEIAETVITGADRTEDINKLRDGYTRLSMTVEQFKKLEVMYQKGGECPACKQAIKPTPE
RMEEIANNIKAGTQRLTLIKTKQDELQGIMNELLQQQRALNAMKTKYEALKGTLQNEVAN
AKRAQAIMEQASAEVVIDEEPVKQLQQQEADLNDKRQGYVKEKYIRGIVTDMLKDSGVKA
SIVKRYIPYFNKQIAYYLDLLGADYQFTLDDEFNESIKSLGRDDFSYASFSQGERARINL
ALLMTWRDVTSKVSGVDLSLLVLDEIFDGAMDKEGGFAVRALLDDIEGNVIVISHQDLDP
QEFHRHIVMSKVGRFTKCKIVNNDY
>RB16p056nc_RB16 hypothetical protein, mobile element not conserved in RB43
MITKNWDDEFQAEIRRRFYHVNGVLYHKTESKQTAFSPAGYYFKPGDMVKCHKTRKKTPY
LQICMRYEGKSNYLYVHRVVWFLEYGYQVDTIDHIDLNPLNNDPSNLREASTQQNHYNKN
GKPNTSSTYKGVSWDKSTCKWKVGIQHNKKKIHLGYFDDEVEAAKAYDAKAIEIGGQYAR
LNFHDYVRTRI
>45.2_RB16 hypothetical protein
MIMLEREFELMTSPEAERFYLHNELLEEKHVVSMEDVKEAFKDNQLELTRILNNKSSMWF
LEKIY
>RB16ORF058w hypothetical protein
MINEKMTHREALEILGATGTESKAEMSKLFKRASLRNHPDRGGSTELMQKINQAYDVVTR
TNSSGETMMDMRARHAANKKAWEEKLDAYFVVAKNYFSTKFNAQEFAEYFTKYTGQPTTF
TQVVKKDTISVSAVFRFTSGDAHFDFAFYCKPEEGKGLMSPDASALGSVSVNTLVLVGTK
KHKMASREYQWGKNPDKITPESLFPSKKLASIFSPTQKNLKFKRADYMTSFRKHLDAEIS
GNDIYVPVGDLKVRFYRHVMMRKGAYVFSAVYDPAVSKFRSAANLRGTMFEDEDGACLDM
IIDTFKEMQKAKPNVNGIVSIIDKMNAEFAAGHRSASFVKRMAQQAAAPKPEEKPKRTVN
RISKDDYFNALKQAGATFRSNYGEFDNGAGLTFHFKREISNRKGFWSFSSFNFMHSGQSH
VEWLKDIDIDEDSKGASIGLMVDTLKQLRGVADWYTARKILEAMRDNFKAGKFSAPHVKK
EAEQKRTEAQAKDELGAQPTKPQGAKKEAPAVDKAHEAQMDREKSQMNATIRSMLSALVK
AGRKDTPEEIKKAVDEAIALWRLKH
>RB16ORF060w hypothetical protein
MIIQVSVQGNTLTVTNSIMTAMAACRDHVMSNPPVTEILEIDVWEDGVIEESFGFTPLEE
DLRKMEQWLWQTVPQ
>RB16ORF061w hypothetical protein
MANCTPMKLPKHTTLLTREKLHSVEWSPLDVMVFDLESKIINAHVNGLSIFSVEFEKIRG
YNEACKDKLRVMVEAMGYIVTIEDNKMWIAL
>frd_RB16 Dihydrofolate reductase
MSKVKAVFAVGHDMYEVDYAFGYEQGLPWGHCKEDLQNFKAETANSVLIMGANTFTSLPG
KLPGRVHCVLSASGQRLVTKNGNTADYIIHGGGLSAAIDVMKATHPDSDVCIIGGKGLLL
EAINNKLVDEVVVTHIYGHHAYNAPAFKRDVSFTVPEFCEAVLKYELTDFKIQQIESNER
VRKIIVDRHTKKA
>td_RB16 Thymidylate synthetase
MKQYLDIVNTVLTHGTESTDRTGVGTLRIFGMQARWNLAEGFPATTSKQLFFKPCKHELQ
WFLEGSTNVETLRKMTWGEDSDKRTIWDDNYENQAKALGYTHGYLGPIYGHQWRSFGAEG
SFSGVDQIARIVKELKEKPDDRGIIVSAWNPVDLDDMALRPCHCFFQFVVINGKLSLQWY
QRSVDVFLGLPFNIASYALLTHIIADICGYEVGDLVWTGGDVHIYKNAVEQAKELLKPER
APLPLPTLYMPKVNSLLDLDQEFFDSIHLKDYNHHGSLKAAMAV
>nrdA_RB16 Ribonucleotide reductase A sub
MSDIKTVVKSSGVSQTFEKEKLFKVLNWASAGKNIDVNAFLENVVDLLRDGMTTKQIQAV
AIKYAADRISVKEPDWQYVAANLEMFALRKTVYGQFDPIPFYEHITKLVEAGKYDKEILT
KWTKSDIEYFEENINHDKDFEFSYAGVQQLIGKYLLQDRTNGDIYETPQYAFMLIAMCLH
QDEPRTLSAFNHVVDFYNAISDRKLSLPTPIMAGVRTPTRQFSSCVVIESGDSLGSLNAV
TSAIVKYISQRAGIGVNAGHIRAMGSKIRGGEAVHTGVIPFWKHIQTAVKSCSQGGVRGG
AATLYYPIWHLEVENLLVLKNNRGVEENRIRHLDYGVQLNDLMYKRLINNDYITLFSPDV
ANDRLYDAFYQADQTEFEELYTSLEKDPAVRKKRIKAVDLFQLLVQERAQTGRKYIFNSH
HVNQQGSFSVPIRMSNLCCEIAIPTSPLDDDDKLAGEIGLCTLMAIVLDNADISEFPALT
RIAVRALDNLLDYQNYPVAAALKAKQRRSLGVGITNYASWLASNYCDYSEAYAGNVHELM
EAFQFNLLVASMELAQERGACGLFHETKYAQGLLPIDWYCKNVDELASPVYNCDWEWLRG
EIKKHGLRNSTLSALMPCESSSQVSNSTNGIEPPRGPVSVKSSKEGSFNQVVPNQNNQID
FYDYLWTMAKRGNKGYLAHVAVMQKFVDQAISANTNYDPANFPDGKVKSEIILEDLLYAN
YFGIKTLYYHNTRDGAGEEEAEDSCEGCKI
>RB16p064nc_RB16 not conserved in RB43 ; hypothetical protein
MITQSRLKELLTYDKETGIFHWKVKLNNNHDITKPAGVVYDGYVRIQVDGKKYRAHRLAW
LYVYGYMPELIDHKNGITTDNWIDNLRIASCTQNQYNSKIRKDNTSGIKGVSFHKRTGKW
QAKCRVDGIVHYLGLFHTTTEAESAVIAFRHKHHQEYSNDGK
>nrdB_RB16 Ribonucleotide reductase B sub
MLTVMNTNPDHKHLEQPMFFGEDTGVARYEEQKHRVFENLTEKQLSFFWRPEEIDLSIDR
MQYAKMPEHEKIIFDSNLQYQTLLDTIQGRGPNLAFLPIASDVSMETWIETWAFSETIHS
RSYTHIQRNLHIDPSKEFDKILRNEAIMKRSASMTKYYDDLIAECHELKNIVLKIEMLTS
HGYPDESIAEYEKKRKEQMRKCKIALYLCMHAVNALEAIRFYVSFTFTFNFAEQGKMEGN
AKIMRLIARDEALHQKGTQSKIRLWQMGKDDPEMAEIAFQYEEEATQIFLEVYEQEKEWA
EHLFSIGDVDGVSLKSTIAYIEHLTDQRMRAVGLQSPFKPSPNPYPWMNKWLKSDNVQVA
PQEVEVSSYLVGNLNTEISDEAYAKWRQKYA
>RB16ORF066w hypothetical protein
MIDAIPVYTGVHHNLYAYLAGCVDCDGWISEKGKNGYLVGLTQHIQLWDDMVSIQSDLIN
DGVDAKLYERTSRTGLGNTLMCNLIIQKSSDLLILLPRIIPYLRFKKQKAVDAYFNLCKH
SDLNASSSDNDMKGSKRKYWKPEEISELIRLHSEGYNNPAIGIKMNRSTDSISHKLHRLG
IMRNE
>denA_RB16 Endonuc. II restricts dC-DNA
MESKVYRMSLDKCGRIDRSFIKCGELRNCVYCIEIDGVIVYVGKAKDMWKRLDTYRNSKY
WREANPSNILKTARLEMAIKKRKRVNLIVTTHDENTYHNFEINMIRKINPEWNKQHYDKA
NQKPENTLQPINEVV
>rnlA_RB16 RNA ligase; catalyst of tail fiber attachment
MKLCNETECFYFIDQKTVMQTHVRIFNYRMASYSDWLKPGALECRGIMFAMDGDTPVKLV
SRPMEKFFNYAEVKAWEALKEAPVTIGDTVVDVMIKEDGSLISTFCDSGYLGVKSKASVQ
SEQAMDAMSVIQSNRALFDRLTELVVDGFTVNMEYVAPTNRIVIGYQDPAVVILNIRNND
TGEYVDYQDIFADSVLRPFLVEREKIEVTDLDAFITEAYTKEGFEGYVIKTDKGFVKAKT
NWYVNLHRTKDSINNNKDLFLNIVENTVDDLKQMFLDDMYALKKIDAFETLFLDSLNRLT
AKAFQSIEDTKGKSRKDYAIALSSDLTPDGRIIFGPMMRYFDDTDKQKLVDNIVALMAKN
YEQFIPEEYK
>pseT.3_RB16 unknown funct.
MTLPAFPKLTSLVWPVLVALSLAGLLYMTITLKSENDQLAKDIKELRDDVKKVKETNNTN
TVIYVEQKAKDQQLVKDAGRKDLLFKKPGLIEIKINKSFEEYMRDFEK
>pseT.2_RB16 unknown funct.
MKITTLALVLGVLLVGCAEKPPEKILPTLPAKVNPVDVKWKVIAEVREIDGKKYLVMPFD
GNPYVALSYPDSLIFRSWMNDVKRQKDQTDNILCAVGYSEKCKLRDSK
>pseT_RB16 dN 3'phosphatase, 5'polynuc. kinase
MNLFITVGVPGSGKTTWAKEKARQLGNTLTVSRDDIRRTLYCAGGDLTGYRFTEEKEKLV
TQMQTNIVLSALGHGKNVIVHNTHLKPGDHIFWKELAKGTGAELHFEYFDVDIVELLKRN
HKRGVNALPVSRVWEMFTQYRKLRGWVPAIQYADPNKPKCVIFDVDGTLTKVGQRSPYDF
TKVIDDPANPPVQELFRMYKAAGYACVVVSGREGTVQCAHDTAASLIGYDVDLSDGIFMR
EEGDHRHDFHVKEQILVEKILDKYYPVLAVDDRDTPTGMWRMNGIPCFQVDYGDF
>RB16ORF072-073w fused hypothetical proteins
MIERENVNVMVELGDRVNVDNPVDLQLKLNQLGQRLVDRLPAGYNVKLVRDGQFSFLLGI
ISQRGIVEQQFGIQWNPVSKFVTWAGVL
>RB16ORF074w hypothetical protein
MNEAKKIHQAWLLMDTRMVRYGCVFGLVDNDPKLDIVTSPVVEYEIPSDNSYVIVKTRSG
STYHIVEPDNNFLKDLLKYMGDR
>cd_RB16 dCMP deaminase
MKLLHMIRAIQHSQGSRCISTRVGAVIVMNGRVVSQGSNNTVDSDCRCADHNEHMLNDEG
KLKAVHRPEHSAWSNDNEIHAEMKALLSAHTNGIMLNNAELYTTASPCPNCAKHIEWYVA
IGAITAVYYLDKYDRGNDEWISRLQKYGCRVEQIKREELEPHINFSNLVFNNNE
>31_RB16 Co-chaperonin for GroEL, essential
MSELKVKASFEYVIIEATARPQGSEIVSSTGIVVGVRQHGEQPYFGKVVSVGPEVPEENA
KALLGKMVPLPHAQMANVPDPDLVAGYISEKEAKEKETKYVSAHYKAIQAIYEI
>RB16ORF077w hypothetical protein
MAKSIQAIIADTVSKSKKLFDKGEILEAPARIDVMTAMIIDAHQGKLKSRTDEVMAYIVQ
FEDVCKYAKDVDPLVREIYRKQF
>RB16ORF078w hypothetical protein
MKGLQKLFDLTPQIREITTSGKSDNEINNALMKFFTEEIDDFETLFRHALEAYSVNGFFA
SPQVNSKKQCHRRFFDWSIVNVVRRTDIEPTNHQLMSVDSAVFIIQYLISGGFKSNDIPF
TNEALMEEFAEAHKYIKAIR
>RB16ORF080w hypothetical protein
MRFLKYASWLVLVPLDILSGVLAILLAPFVVPFYSEETGHLPKGFRWMETFDNPIDGDGG
HIRRWANIRYHLGALGVYTQRVGWLWRNKAYNFAYHVLGREAQSDFAWKGNPKTEGGSDP
SRHGYLLMWNDSAWGLYVFKPWLKVGKVQFCLRVYCGWKLKQEVTDPNGLDRAMLAFHIN
PLRYYVVER
>vs.6_RB16 unknown funct.
MKAYQILEGLHTGTIYMEEGNDVRVVVSKTLEMDSVIGKARVAPFAKREVDIEFQPTVKV
EGGQHLNVNVLRRETLEDAVKHPEKYPQLTIRVSGYAVRFNSLTPEQQRDVIARTFTESL
>vs.4_RB16 unknown funct.
MAIEDVQGYKPHSKEKIDKVNRIKAAEIALGEIFKELDEEYSSDYAVSDTDSFTTEELDA
MLERVHQIQLAKDRLKEASMWACRAVFQPEEKY
>RB16p081nc_RB16 not conserved in RB43 ; hypothetical protein
MKTYNMKDLVCFKTRREARAYVLAAGKNTSAVIDLGTDKEVGARWAAVVVIAAPVTPVKT
LVLGARKAETLKTSTCGAGGVHNVTVIRKRSFNRVGV
>30.3_RB16 unknown funct.
MNIGSGDSYPSCALSNFAPHPFTFDGVECASMEGFLQSLKFSNPDMQAHVCTLVGKAAKF
KGKKKKWYRDQTLYWKGMPIHRESEAYQILIENAYNALFLNEGFRRALAATGKSTLTHSM
GKNKMNETVLTEREFVRNLTRLRDLL
>RB16ORF091w hypothetical protein
MIGYKDYDERVECAFLFKGAINPLALLHAQGALSSTLIMGVIYKAGVYYVTIGANNINVI
NSYVEKCKLKDIVFDKVEMDVPGFDAVYMYKG
>RB16ORF092w hypothetical protein
MGYVVYFDCSDLDPFVLQQAKKYHQDITGISVTNDDMLCIEFDYYRTFERDKFLADIEAF
KSTLFFDRYEVKS
>30.2_RB16 unknown funct.
MKPVILTDIDGIAVKWQSGLPFFLSKHNMPTDIALDMVTDEKFRDMTEIFGCDHQLAKIL
MEEYNNSSFIRYLSAYDDALIVINRLKAKYDFVAVTALGTTPTASLNRIANLNTLFPSAF
KEVCVVGHGETKVHRYLEAKAKYGDRLVCFIDDLAVNLNECHNVISQLPLFHMLRGERSE
PSVPHTKVNNWHEIEKAIENS
>RB16p086nc_RB16 not conserved in RB43 ; hypothetical protein sim to T7 gp3.8
MKLKKQLRTLDEETQGIENLLQCIRVEPETGKCFWLEKRSNKIPAGSEAGSFHKSSGYTR
IKFENAMYIRSRVIFYYVNGYLPVMVDHVHGVECGDMISNLRESNQVTNQQNRTRNKNNT
VGFKGVSFNKKSQKYSAKITLHGVTKWLGFYDSAEEASEAYKAKALVSFTHNERYLNDLT
DSE
>30_RB16 DNA ligase
MILQILNELASTLKTSEKEAILKRNAGNDLLKEIFRITYTKQIMFHIKKFPQVDGKPGTT
PLSNAIADLMSDLATRKYTGNAARDRLLDIVSSVNENDREVLRRIINRDLECGAGTTLPN
RVWKKLIPEQPQCLATPFSEKALKRIRFPAYSQLKADGARCMSDLLEDKIRKASRAGNEY
EGLLNLDKGLKKIREYLGYDVVLDGELIYVPAEKTAVVPSNSVPFSLAGFMGDDDDSVSD
LVADVRREATENETQAEAKREEGNGIVNKSLKGTISDEEQRNIVYVVWDIVPYEVYYGDA
PSVQPYCDRFSILEGALAGSGVTSVKLIPSILVQNYAEAKKDYNNYRNEGKEGSILKNVD
FKWKDSRVADQVKLKNKTPIELRIIDVYEHTKEAHKVGGFVVEDLSGEARTNTGSGLTDT
DYRYDEDGINRVYIPLEERGELDREYIMANKDDYIGAIVEMEVDGLQKSKTRKKGEPEFS
FFLPIIKKIRRDKTEPDDIHVIFADLF
>RB16ORF096w hypothetical protein
MQITKELEGKVIVLVNEDRLAQLGNGGEKLPADALESLSKMRVMRVTDGWVTCLPLNDED
KAVYDAQADSWDIEVPLVNIEVEECYEIEK
>RB16ORF097 hypothetical protein
MKIMHTANQLQNGNYAIHDAIGALVGVYLHGIKLLEVSGNTFYGVENIEAAMEIIGDLK
>RB16ORF098w hypothetical protein
MSKKLEIFETISEDPNHRWCCAKTGFDAAWGDTPEQARKNWEHQQLFFACRVPTNYEGSQ
LLA
>RB16ORF099w hypothetical protein
MKNKEYDPIEVKERLSVARRFLESIDPDKLGKCPDTICLNCGRSVMVGKCCDNQNIVIMD
RKEVSPEVWDRIQEIIKNPPEPTKRLRELMSRKPRYEK
>RB16ORF100w hypothetical protein
MKNEPSKTVRLIRWEGNELRYEDGDREFVHEMLAHNLGFKNAALVMMQQTSDEDTWQCVI
LDLDKNKEYTEDELFALTENATARQKCFMIDMPRENYENIKKARKQNKNNVFDLFMGYHE
ETTA
>27_RB16 Base plate hub sub, essential
MSSKVINRVVSVKLYPTYEKFADNVYLELLPALVSMSEKTIINGTSETLMQIYDNQLIYQ
LTEKPIIQVSFQYNQTLEQHYYGVLYSNVETDDMNRSILRLNLSPVHTVFRRKFSRSFSN
NAVQTITECMTALYNDMKLITPPIDASNVRIPPACLSGTYETVFDYIRDNGQSVDSSDFC
YLWEDGSGIFMKSNTEILAQTPIKAYKFNVSNPFLGDTLVFTKAEYITHKDNTTLLVDAS
FFSFSMTDKKLYSDILASTDIENAWITMNRNAVYENNFQNPDKQGQPFQAVKCQLLSSYE
KRIKFDINQGRMDVKVGALIEVLGDEYSGKYLIVECVRDVSKDFHLQTLECVQVAAATND
TSKTSEA
>28_RB16 Base plate distal hub sub, essential
MKEKKNTLDKFMVTRLNIKNSKNKVVTLPTGEQVTIPRLGYRHFTQIKAMKDPMQLLEYI
IKEIQPRELTAAETEFLLIHLHYHNDDKAMAILKEIGINLDDMKISEAKYEHTFDNLRLV
FNKPTLMLDDLALLLKEAYDNGKPIELTDETRIQLINCLYRYEYDDVKRGVLQEVYIVHE
GKTIKGLNIIGE
>RB16ORF103w hypothetical protein similar to sp P40328 26S protease sub, YTA6, Q62209 SCP-1 prot
MANNPYYSDEQRRRMQNPKPQPQPTVRKINATLDKASMQELKDINDNTLETALNTLDIKD
SVKSFEDRFKEKFAGFQEQYEQDQQPLADQLPDFVGPSRPSVLTDNSTNSVDNSVSVSNQ
NNPFSKLEAHTSTIADAITKFIELASKKPEPAPEPEPVPEEEPEVDKKKKKIRDKDKDEK
KFSKKVLFLLDAIKSNTSSLLSRFIGYSLETIAKFAKWTLIIGSIVFAIEVLGKVIASWF
NDLLNDGEASKQLFGSYFNNIKALAKSIDEGLDKLGDKDATLAEKLKALLVEPFKILGNT
IKTAITEGIGNLIYALGEYTGSETITNAGRGMKVSALRDKQKYGLEIDPDDLIMLKEQEI
QDQKDKITQAREKVVEQVKATQGMFSYGFGQQTEAQQVQSKHLEELRNQVDLEEQITKEK
EKELQMLKDNPNLLKEQVLKENTANAKRVDDAKQVEAAQKATKPKAENEFDRGDAILDKD
EITGKDKELMEKILESLEEKNNSKKLDEDDSERYRSMLDQWQNKIAVVPESSASIDKQPE
PVRAPVEATASNNVQVNNKTVNNTVQHSVQRTERKPLIALA
>48_RB16 Base plate; tail tube assoc., essential
MKIKVLQDTVQSFAEIKNAGIPSGGATTTKNALTQPIVTAEFPSQRAAGIDNAYNASSLY
NNGLLFTAYEFTGGFAPGSKDNYRSLRQAAQNAQQILSANTGNVRYKQVLNTRTMGTLNP
ICQILLPRSLNDNEVNSHRYQDATDSIVAKGPSRVVSNVIWGVIESASGGILADRREAVD
VGTKAAFQGSDKRTKMYYNTFVIESRYDLLELIKIYYLFTVLGYGTTSGGTAAEIAELAK
QTINKSSTTGAKLINNAVAGNGPTPTVSNGSIISDQMVDFVINIEVIKSPPVWFIRDFQT
GDSLRFPHSTFGPAGITSVRFGRTMDNIVNTLRESPNTPISVEIEIQFMELIDMRQDSIF
DVQY
>54_RB16 Base plate-tail tube initiator, essential
MFYSVDEFLSGMANNDFQRSNLFSVVFATSPASRILDSTIGSIRDTLIDGTMSSINANNP
NEFMNAITGGVRKLFSYTVDKAIMSLNKTGFSKIMGALSPRLVTSLFGDSVYGQLLTEFR
DKMMYNMGLSIVGVQLPGKTLGYEYVYNGGVPQIRFTRPENGELSLTFRVDSEARNLKVF
NEWISAIRDDITGQFAFIDEVSSAIQVNLHNRDGVPHSTYIFQKCLPVKVSSPELSYETN
NEIWTFTVDFAYKTAWIVEADKEGWDGFKQSMIEGAAVALRGVVSGQ
>51_RB16 Base plate hub assembly catalyst?, essential
MIDVIRVKLPCGVKRFPMFTVRDQLSFLLTSADMEGKTLTEQQQILDEILDILYPGYSKT
EQENIFTKVYCVSFGKNVIKIRIKNKDSYTETFMQVKDYELQNEYALDDSLTLGFRFPKH
RKSSEELFLECIQYVKQNDTRYEWEALDEDTKNAILDLVSITDMENIVKMLRKSCHVVVR
DLEFSDLLTLYKILFNKSELNEFFKTNYLLNKNEVHIEPIMNASPMERSIYVAILAEDLK
QRQNTNA
>26_RB16 Base plate hub sub, essential
MRKHTPKHIQKYNVTYRPLTIGDVNDTDNFILEGKVFKHQRDYVYLMALFDSINTDTVDL
QIKCPDCGELIKFTLNRHHIMIDEFEEKLFGNEIKIAVSPYVTGKEELPDLIKFVVIDGE
QILWEDCKESEKEAVLDSIDYPVFKSINTALEAPAMVANIPVGCSCGYKHIVSLRGLEAF
LKVVG
>25_RB16 Base plate wedge sub, essential
MAVNLRLLYSDIDPNLTKDWNKDVAASKGAAAVKNSLIGIVTTQKGTRPFDSNFGCEIGE
QIFENMNPLTAESVRTSITSAIRTYEPRVYNLNVEVIPQYDENAITVTIYYSIIDEPEEV
EKIKLQLSSS
>RB16ORF110c hypothetical protein
MKMNYVRGGIMALLLKGVSRSENRMGMGPIGKVWSVNIGGDCIGYIGNDGLSRVYLAISS
GGREVECGNFMQALAQFIDTAITLVEKQGCIERRYANKIGMIEYSNFCFEVEEVRYDTMD
EVYEYVLRGEEVIKSYNGTKVINNRSFITPFELRYQQLMGWIVME
>RB16ORF111c hypothetical protein
MNSVYLIEETIIQPNGGVYEKNIVCAALNEQEADHKVKYLNENAVVCQTYSGYSVAYAWK
EVSLETQPSWLINLKK
>RB16ORF112c hypothetical protein
MNAKMKFVKDWRKGAVIGESYIIVDIESNPIEGFDVLEVPRYGMIEAAEQAERLNGYVLH
IIEAIEKELA
>RB16ORF113c hypothetical protein
MAYVPKKEVFLNPLLGKSLNHIETMATIVKDNIFKSYTRQRSLSENTRFHKIINKMFTAP
VHIQMYLVGEEAYVLVFSQSRNELVGYFHKNNLASIIMLDSNPNFLNTESSGYKESTKVT
TRSKMRSLLTNAKRFVYSDKRYINQMLKYLDDVPDHDKNVYKPVVEVTTPSVEEVAPALI
RTKFVIEIEADDLERACTSLSSIGVNFMLYNKFN
>RB16ORF115c hypothetical protein
MITIVYWEELESEFSEEAGEMAAVDGDSEMLTVTESIETAFAKIKYHQEATEGRDIQYML
TFWLDGEILCHAMIAENTSVDTCREEILKYVKSFMH
>RB16ORF116c hypothetical protein
MKIRSGFVSNSSSSSFIIGIGLVRPGKEEEVAKIYGHENVESLLDIITDDQRPKWGIPQI
DGDNITLEAFSYHSVDIRYIWDKMKESGVDDLKVVHFNERGDEPEWDDECGCYNYSYYED
ADAFGPELEKKYNLLRDNRELFIEGEVKCGGGYDG
>RB16ORF117c hypothetical protein
MTLFFLLALGVFVVGSAIAFLAFNKREFSVCFIGLIVAVAPLVMSYNIYQEKIAENAKYE
ARR
>RB16ORF118c hypothetical protein
MSRNIFWDEVKQGDILYLAEPLAYRENHDKNKPYAPMLPEYVVVDNDDAYEKGVINLAGF
PYKKGAINLFDNDADFFSHVGNIDDAGFDIDDVREAPYVFSNYYKIGGHLRSDNKTVLYL
DSLLSGMHNFNFRKKGNNEELFNLFEKFNKTGKLLPTEMAYIINRLVKGLHQTAIIYHDG
DTEQAMDTVIKTLLEKSKQMDTLTK
>RB16ORF119c hypothetical protein similar to sp Q55874 Hypothet. prot. sll0103
MSITNIEFKNAVSKPTPTNHVFVCDVSGSMYSELPKIRKHLKANLASLVKQDDTVSILYF
SSKGDYGTVFRGEKVSNVSDLTNICTAIDRYLKPTGCTGFVEPLNLAAEIATDLQSENGN
LNSLIFLTDGYDNCWRTDDILKACAVLPLTFNSIAFLEYGYYVNRPLLEKMAEATNALHK
FVEGFDAYEPAFAEIITAQTSARIEVKVGDATHAIYIDEGRVYVLNAANGVVLVPEHIKN
IWALGDNAINDIDGFDPATMEGEQVLYVVLYHALHTMNPDLAWKVLKKVGDVRLIKAYDN
CFTKQDYSNAKDLIAEAVVDAGKRLIEGVDYNMVPDENAFTLVDALELLAETDTVIDLSS
EHWAYNRTGRQTVQKEDDTLDQLSEQIANAKTPEERKALAAQMVTHEIWTPKFTQTTTKV
SVKHLVGNSSRPNISINTDLQGYVTIPESKQKELGLPEQIETKQVRNFTIVKDGIVNVKV
LPLETDIPTLKNLRASGLTIKPLAKIGEDRMSVLVDFTSLPLVNRAMTRGISGKEYVNDS
IRLEILKGRQKVMKFFRDDAIGLRNAEGLKQKYGEAAGEWLSEQGIRDYGFSPKVTRTDS
TDVYMSKELNLKIKGVSSLPAVAATVAKRAEGKKKLNNGDLIILWAYDAVKAELAALDKD
KVIEYLDKETKATINEVRALNKRLSRVMYGIVVGHAWFADMDFEETKVSVKATDIIPHKF
WEGATFDCEIVLEEKEVKL
>RB16ORF120c hypothetical protein
MKEEMMYTKAATLKAHKLGEPVTIEQHLPLPFDLFSLKKYIERFDLNEYDVDVYEFKNPH
MYSLGFNMQDFNVNSVEDFYKAIGGKLGCEPDQQTISEKIQSILNAHKTTKY
>RB16ORF121c hypothetical protein
MKIRSGFVSNSSSSSFIVRFPKDPTDINNLREMMGECSPNCGYYNPPLTSEEVVQHVHRD
LGGHMGNSFESYYDDKRYDWETEDSAETRYRSNPQIALAYDGRDWYDLETEEKDALIKMW
LYEEYNTKYGNQNGVFIYEFTYSDECGPIGTQLEHGNIFRNLEHTSKSHH
>RB16ORF122c hypothetical protein
MKIYSIEKDFYDGRDNESDCVCSTVSLDVVLDYIRNNPLDDCCYHYYVTIFDGFTGKKTH
RGVVCYNHTQSLKEIKFEALK
>RB16p113nc_RB16 not conserved in RB43 ; hypothetical protein
MKVKNSERWEKTKEMFFIRRNRKPLKRGYDDIDEALIKFNEIIRSSVYRSGEHPGDLWEL
VAKDPYSNIVLKSERKGKIS
>RB16ORF123c hypothetical protein
MIYVSSYSADYEFTEIVHVSESLQNCIDALNKVDNFPYLGDNITIDVWENEKRIAKSSTY
GYRDVWDEESQQYKEIPVTFEEIMANMRQVNEG
>RB16ORF124c hypothetical protein
MVASIIMLIIAVVGMIVVFGYALSIRKSLGLWGTVFVMGIILTVFPLMIYDVITDLIWWV
RVL
>RB16ORF125c hypothetical protein
MTYNDLVAGNAYKVASANLLKDYSNTKPEDVGYLLVEVRFVDGGYNCFYWDKSFSYCLFG
TKFKSDYLLKSEAMLKENNPVFYAFAESVKHIFGH
>RB16ORF126c hypothetical protein
MTDYRKRASIAEQENARLREQLKHRPKYEWFVEQARKALKQADTVPPQQLIPQIRQLKEA
SERRKAMRNQPEIPIDTVVEWHYNHWDNDEWSASQGVLKYRKGNFILIELNGEPIVLDGK
ELTMRPYKERPETKFFKKVFASS
>RB16p118nc_RB16 not conserved in RB43 ; hypothetical protein
MTYEKLYAFLLEHYRRSRFEGRGMDKAKRITEMYMEDLQKYGCSYISRHEDVRGQGFKFD
SDLNIFRGDYVEYPNNAGNLTHIF
>RB16ORF127c hypothetical protein similar to sp P24581 Cytosine methylase NlaX, P34877 methylase ScrFIA
MKIIDLCAGVGGVRFGFDNAFGGVECLLTSEIDKHAQQTYIENWGDDNLQGDLFAIDENK
VPDHDILLAGFPCQAFSKAGLKLGFDDARGTVFFEILRIIRAKKPRVLFFENVPELLTHD
KGKTFKTIYGLLEAEGYNVFYQRLNTKDFGLPQRRERVFIVCFLDDVFFSFPVPPRTPTR
VGDILEDADDSYTLSDNAWKGFRERKERNKANGKGFGYQAVTADSTHTGTITAQYYKDGV
QCLVLQDGKNPRRLTPRECFRLQGFPDSFIIPSSKKQAYKQAGNSVSVPVIEAIAKQIRK
VL
>RB16ORF129c hypothetical protein
MSDIILHLKDVRVGGTEQHPDSVTMEQAVVQIMRDSLRLEVDEQTHSEYVGGYDGRDMYE
DRKTVKVTLWADIDEQSYKIDEIDFDA
>RB16ORF130c hypothetical protein
MKEVNLYTGYIDKRDVRRVEDVVSDMLTLHIDKTDEEIAEKIREALYAVFARVYSVEFRT
ADKYDTSDYVIRVEEAQTEKFDFYTWGSN
>nrdC.11_RB16 unknown funct.
MKTVVEMVFGSFLYGLNTPTSDKDYKGIFLPHPRDILLGKAPKTIDTSTGDKNSKNTVDD
VDRQLYSLPKFISLACDGDTVALDMLHADDSKLIANSEIWQYIRANRWRFYTTELTGLFG
YVRKQAAKYGVKGSRLAALREVYDVLQDTDNAHYDENASSLVNTKVGDIKDQLPTNEFCR
SILHYSEKGGMQNFYEVLGRKFQFTITVAEMKKSVYKLWDEYGERARQAEANNGIDWKAL
SHALRGGMQLVQIYKHGDIVYPLPESDLLKSVKAGNVPFAEVQEKLEEVMGEVERLAAIS
TYPKEVDREFWDNFIELVYKDHVMRYYK
>RB16p123nc_RB16 hypothetical protein, not conserved in RB43, sim to T7 gp3.8
MKCHGRWKRTLEDERSEIDSLLEILRVDVDTGLCYWKVHRGSRATVGSIAGSTNSFGYTA
IGYNGKSYYVHRIVFYVANGYLPAIVDHKRGVGNGNGKDNLQEVTQQQNTMKAKTPKTNK
SGYKGVYFDNARDKWIAKIKHNRKDMFLGRFATPEEASVVYEAKAKELFGEFYENRS
>RB16ORF132c hypothetical protein
MRNLSDVKVGDTLYDCGIRSDTRQNRKPRTLYVHKVARKYIYASTSETFDPKSYTNEKID
RTFGRTDGWMGYTVYRSEEHYKEMMYRKELCAKIQPMFGNSYTVNVPEITTENLKAIAAI
LGIEE
>RB16ORF134c hypothetical protein
MKHARSVLMGDVININGNDYYVAEINTKGNREILKLDIVKSAMGKSLTIELVHNTKTGEN
VITPVLSKLPVFYCEKKKCWKMK
>RB16p126nc_RB16 not conserved in RB43 ; hypothetical protein
MNKTAFIKTEETKIVRRALIPGDGVFINHSLSRGFKEPFTVQSVAKDIKLGVPFTVYVFV
SDNRSTTGSTIIATIGSGDDHRLLSDSVYSVNIHSIDSRDCAAKDKTVDVDGNNVLSFSL
NKREKVERPVAIGDILKTERRTYQVEYIAKDGSLLCRMYSRKDKDAYQGMIVIDGVDRSL
MSSLYTKVTFK
>RB16ORF136c hypothetical protein
MIKHPYCLVSRPISTGGLPVNCWQLIEEGDAFLNTRGDKVFVYGVDSIENETMVITDEKT
SEKYTLTSDHDCRNFNVYWKSDEEFERKSL
>RB16p140nc_RB16 not conserved in RB43 ; hypothetical protein
MNTINVSKADVMKATIIATEALSFMAKKAGVDSAVILMEITNNPEGNTARYFKDLTSYAM
EEFK
>RB16ORF138c hypothetical protein similar to sp Q55928 Bifunctional NMN adenylyltransferase/NUDIX hydrolase
MKYKFDKAVVIGRFQPFHNGHAAMVRKALEESKAVYILLGSAYAYPNVLNPLTATERERM
ITSWLLSEFKYEDVSRVQFKPIPDYLYNEEKWKTSVRTAIDETKGDNIAIYGYEKDADSY
WLKAFGWTHVPVDPVKVDGKDLSATDLRPTIFLHKNGWDEKIARYVPAAVVGSLNGWMMT
DTFWRLYYEFEKWEDELEKFKAYPYPDALNCCTGDSVVVCNNHLLVIRRKFAPGKGALAL
PGGHKNANETFLDCAIRELLEEVRIKVPEKVIRGSIRNSMLFDHPKRSVHFSKPTVAQYI
KLEPNNDGSLPRIMGGADDAAEAFWMPLHEVVQRQGEFFDDHFQIVNAFTGVA
>RB16ORF139c hypothetical protein
MNMNTILNNPKKTTLIALGVVAALWLVPNSFTVVQDGTVKTQTFMGKVSPKPVLPGFHIV
NPLADFDTFSTKDIAKKFDKLQVPSQDKFKSTVDMTVMLQFDGNKAPINRINAGDQEQAL
DKYVTEKLLSTVREFGKSVPKAQDLFDAKIQNQLQTAIQQEVEEYARPYGYTVKQVFLQD
ITLPDVIMEQVTNTKIREEQVNAARAELAKVEQTSQQQVKQAEANRQARENDAIANERDA
DAKLYAAKKEAEANAVLQRTITPEMIRWKELDVQMNYSTRYKGDVPQTVMGSDYAGKVIF
DSRK
>rI.-1_RB16 unknown funct.
MQTFNEITERDTTSKIDAFIGTCLMSVTYMHSAHFATGSYSQHKAYEGFYEDMQDLVDKF
TEIHIGITGRYKPVLKVENVLDTVAYLRKIATEAEEIYDAVDSSLKNIMDEIKGLCYQTI
YKLTKLS
>rI_RB16 Membrane pro.
MNIKRISKALMFGLLILSPASHADDSVVPKEFDYYINAALQVYLDTIPPSVNTSELFYNY
MERKWQQKQCKSEPECKRLGLRVATEFASIHRS
>RB16ORF143c hypothetical protein
MSRTYRNKYVPARDKSSIEQIEETKTFSQYYAQHGESPDGLRWYTTNWKHKSGCAYIRFD
KNVNRDGNKAHGDISVMLEIAKKRIDSKVREKMRQELRRMKAGVIGWDENIENANKIRAY
ERSLCWYDIT
>tk_RB16 Thymidine kinase
MAKLYYHYASMNAGKSARLLTDAYNYKERGMNVVIYKPMLDTRTSHTVSSRVGLNANCEL
IAPSMDLFWDIQRQNNISCIFVDEAQFLSKKNVFDLCRVVDELEIPVMCYGLRTDFQLNL
FEGSYWLLAWADEIRELRGMCHCGRKATTVARIDAQCNFVTEGAQVEIGAEDKYVSLCRK
HYHEKVLDKVGVNC
>RB16p148nc_RB16 not conserved in RB43 ; hypothetical protein
MRVQEEKVLKHKLKELGELYQDYAAEDDPDSRNVNQLYIDRMVDEIISFVEKEVEDAVFD
AVAEERAKHG
>RB16p149nc_RB16 not conserved in RB43 ; hypothetical protein
MGLIIFYGTVIAVAIIIWYYVKKPGERSLPEYNDELEAWQLWDDQFK
>RB16ORF149c hypothetical protein
MKKLALLLTLVSGSVFAVDDNRLSELCDHRDIKDTAVCYQVIAEQLDAAYVWGEENAHLY
KRQKLVKQREFLQSEPMMKLCTRAPNKERCEKLRTYLVDEYNAGIGLY
>RB16ORF150c hypothetical protein
MSTSHRVIVGKCGLIKLNALSIIQSVLAELKSKPNVKITQITVDKNSMNAFSIYFEYGEE
KRILFVCESDDVYRNVEDYPIECALYFNLNVWGSNKEIMEIVKSGIRKAVRAGGIYECVN
DSIEDRFVYVLGE
>vs.1_RB16 unknown funct.
MRFKWILPFIFLCSFSGHAKTDPLGEFIEKLPAVQSTLPLQQATVIKKAPANAPAYVKEL
DEITPKQKKVLEYAFRVGNDYDLTTAKPAEKEKSKRLGYHLAAIAWIESRACENTGKGKK
GHHAYGCWQVTVNSASARMDKSYSKRVVINKLESLRGGSKFAIHELEYWLDYHKGDLKKA
LASYNAGFKYTKKEARDYARMVNHTAKLLEEKQII
>RB16p140nc_RB16 hypothetical protein, mobile element not conserved in RB43
MTKSYGWGERTLSEEKQLIDELLEYISVDVVSGTCVWIKSTNRKIKVGSFAGTLRKDGYT
VINFKGKQFRRHRIVYYVSTGTLPVMIDHKKGVSFGDGIDNLQEVTNTQNQQKKSMMKTN
TSGFIGVTWNTINEKWIAQITINGKATYLGSFDDPEEASNAYKKSALLNFGTFYNKESP
>RB16ORF154c hypothetical protein
MEREQKYIVIKMSDFDKLKYEDQLSLRAIARRVERQRSRDGKEPLKAVVVEHDWPEYEPT
WKAIETRVEREESHRKFVSIFDDKERLGFFYVVETHQGRFLITSNAHHSSRLECYSGYKY
RALFSPVCCFDNSEIFFTNWGVHFKKVVQVSFEELVSLYDPNKSISNYNVAEFIINKLGE
SEEPEF
>RB16ORF155c hypothetical protein
MVQVVEMKPKEVNCRKCDSRLSYVATDVREETHTDYTGGRDTYRMITCPICHNKIVVK
>RB16ORF156c hypothetical protein
MIKIIVSPKLITVCESCRTGLEYELEDIQSKTVTIYNGFYSPADYIVKKFITCPKCGSKV
NLNLN
>RB16ORF157c hypothetical protein similar to sp P46343, P77349 PhoH-like protein
MKYVLDTNVLISNPYSIYSYVAPGTEIIITAATMEELDHLKSKEHTSREARLVIRLLSKI
VLGQKYEAITQTGVSLGQTNPALPDSVTLRIVDYVGGEEFPLDKQDARIIATCLQEKATL
VTRDINMLLIAMSKGCPVEQYTGDDTLKDSDVLYSGYIELTDFWNIVDVVGYNGDIALIS
YASFADYKVDFYPNQYILSGGEVVGRVVDAGEFQLEVLPLKHEHLMKRKLMKTIQPRDAL
QASFVDSILDKNIDAVTIMGAAGSGKTMLAVAGAMHLVSAGHFANVMYVKSDSPLSGEIG
FLPGTLGEKLRPSIEPCITSLNILFKDQPEVDKYVEGLLEKGVVQFPSLYYFRGRSIGHP
DPGKGSVLIVDECQNLSNHEIKSIISRCGENTLLILCGNIKQIDNPRNTAVNNGFVYAVE
KLKEYDHASHIILNTVYRGRLAAFVEDNF
>RB16ORF158c hypothetical protein
MFSKFYVDAVKQSRNMHLMRVMEGQADTTGVAVFETALDMGRRSGKTKAAFEIIRQSKGT
LNIYVAPTKQLAVGEAQRFEADCENLMLLSSRQDLTTIFRGRRIEHQAINLIFDECNTKF
DDRWELVQTLMICMRNSNLHPFPYIHIIRLGM
>RB16ORF159c hypothetical protein similar to sp Q37976 L-alanyl-D-glutamate peptidase
MFKFSQKSLNNLKGVKPELVKVVTRALELSTVDFGVREGLRTVEQQREYVRQGVSQTMAS
KHITGDAVDLYPSVLPEGWQKNPKVWLPVLDAMKKAGDELGVKLRFGINWKNDPRLPIET
KFIDAPHIELA
>RB16ORF160c hypothetical protein
MNAFEKRAQLKDIKPGAILYEVFSITGVKAEMGRKHIITGFPYNHRGIGLFVKCITIYND
WENHSRCSLMDRNVLGRNHYNFHAFFLSEKDAREYVDQINNDNLPLEIREESRKMHREWT
IRRADDALWEM
>RB16ORF161c hypothetical protein
MTKAERIINHLQTGFPYQGDLQRDIIELLSQHDGMEAEIKELTHPDVNVFASLIDDVIAI
DADELGCIETTSAGDKVILKQACERIDALHDRLFQLTFPSKNDNPC
>RB16ORF162c hypothetical protein
MSLLNEILEMVEANKEAMKAKDGWVVVSDCFKPSLWTPVYINEAGNEERGFYEAAIFETA
EQACDFWAYLSGEEPFSNYGVCRCCEL
>39.1_RB16 unknown funct.
MFKVIGCVLLVVVLVLLQSSCTDEREAQRILEAQGYSNIQFTGYSWFSCSEKDTYATGFT
ATGVNGKPIAGAVCSGMFFKNSTIRFE
>RB16ORF164c hypothetical protein
MNLSCELSGAIRKLEQVLDDLSAGKEINVSDIEAKLYEWRSALYTATKGNDPLFDEYQVY
EVELWGDKYRFKWPNDAFGSINSLYVSGGYLYATDVSVHDLGISPDNQVDLPNTFSHTTV
CLGAISGFRCGSLGVSWVQASKTNLKRV
>RB16ORF165c hypothetical protein
MTEILDELMYVYRERCSNGRITEPKAKAIIERYWSKLREQDASSKLLNSLMVFKLLIASG
DDMPCDTNSAEEFQKAYRSWGVIYSRSLGSYDSVMWNLMHLDKLIWEVLKEEGIV
>RB16ORF166c hypothetical protein
MIYQSFDDSTTRIRPVPITIDIPAETRTLESLIEKYSGMTICSATAIMAMSERDAIVFEC
DMKGYHTPEDMQMIDYLWKIRNAVVRKILAEKECAEECNRIKSKWGVL
>RB16ORF167c hypothetical protein
MIIVPEIKSYKRLYADHFVYNSNAEVECINYPVNVEHVSWIETDAKIPCLNKTWKPAIKF
HLAHNQSITWAGYECEEERDAVVEYIIGYMNTLKYGKMI
>RB16ORF169c hypothetical protein
MDIIDRAQTVMKAPSLMIYQQGNMRFARSKWYNYNFNVDTGEFSRWGTTFASDPTYAPFP
EILDIEITTKCNGPAGKLCGFCYKSNNPNGYNMDLESFKSIIDKMPWLTQCALGADAQGQ
TNPDMFDMMAYARSKGIVPNLTIADVSKDVAARLAAVAGAVAVSVYKHAGFDVAFDSVAN
LAEAGQQQINLHFMVSSKTYDDAFNVVDAVRNDPRLKQVNAIVFLGLKQKGRGKNWDTVT
REQYKKLVEYCLDSGVGFGFDSCSAPAFVEAMEGHPNFEQYKQYAEDCEATMFSSYINEK
GEFFPCSFTERWVEGGWEEGLNVLEANDFIKDIWEHPKTKQFRNELIGNKDHNGCRNCPA
YAVCGKDMRVHKATETDVYAVELK
>RB16ORF170c hypothetical protein
MMQHEIKTEIDKRIFLEKNKTVTLMHYSTKNGSSEFWRVNIDSKDQGTSIPFDSENLARA
VFQSHVKF
>RB16ORF171c hypothetical protein
MLTFEEYKAKRDQLSNWHREIGRELSAYPKNEMGMTIESIRNTPEYKAKRALCNKVFQQL
RILNGKYIKLYKKELADERKLKRSVK
>RB16p158nc_RB16 not conserved in RB43 ; hypothetical protein
MTTEIDIVVEQLVLEDRKITLSYYSEDGCESWDVTFEGSDFGMGVSFSNEEKAREKYKEY
CVLYGK
>RB16ORF174c hypothetical protein
MRFRPYIEFLRGISEILNREIKPSPLAVELYRLDATPEDAAKDYGNEL
>RB16p160nc_RB16 not conserved in RB43 ; hypothetical protein
MEIIYKSRNYKKEDVAAVYIKYRNVKCEYSGIWGYEIVVEEVNADNKTICSFTTNTDSPL
FTTEQLEQAYELRNQAFNAVRIK
>RB16ORF175c hypothetical protein
MKHIFSNYLNIKFKTDGVNVWWWSNNIGQWFPEFTVTAESLERSLKNGNASVISTNC
>frd.1_RB16 unknown funct.
MKLVREAIKLGNEYNGKWYFIIYDDNAEKLEKVEDALRAMETGASVGGEVMTWENYCDGC
PCYNDGFGSGFWVEIEDVPEFKAAWKIAKKMA
>RB16ORF177c hypothetical protein
MILDEEFEMLNRAIQQVKPVIGDKWDGTNQPGSITGNVNYGCGSNMKKRAFTIIGPKAVQ
SVQENMWLESLMQYMVSFDPDTTERLLKEIVRLHQENDKLAGERDHWKANHECEVSRARV
LKERPDMPLERVNAYNRMVELEKENEALKQRIASLENVEMTRVMIDMASQRGHEQTQMLH
EILRYVKAHFKDPGYY
>RB16ORF178c hypothetical protein
MQHVNLNPKMKKYLDRRHDNQTSKDQELAFNIETAKLLTKMFRRFPNKVTHTSTHMRVEL
ADKRCIMVRLAYGLSEDGYNLVMGWTSMIGNYVERNDIEFNMMRGDLFQCPVDTIHIGSL
YAILRSQYELWDMK
>RB16ORF180c hypothetical protein
MNMNKNIAAVVGCEVSNAERYDDGFSFCVPTELDAYKAAYKYRTMPMVNVTYSPNIEMWV
VQVYNKV
>RB16ORF181c hypothetical protein
MNKDEELNVDSVEPNQFIIGKEDHELLQAVKNLLAYAHIRVPNGDNAKLEIACAGYGYMA
NADKIISYSASRTRELVQYRDKLSEELHQTQTLVDQLPKKFE
>RB16ORF182c hypothetical protein
MSKDDIPARNRIRERITFRSREHAIMVGSYIHWWKNKDLDLNPSYQRPYVWTQKEQDEFL
TTLITGFPCGIIAIAVDSEFNESHWVEVIDGKQRLTTIIKVYEGEIGIPMSDGSRLFWDD
MQRHEQRAFENLSLPALGLDECNKKDRLEFFIKLNFAGVPQSQEHMKRVIEMYKAAK
>RB16ORF183c hypothetical protein
MNGKRVVVTGEAKHNEKGQHLIINNDRGDWYGATNVNNGYATIVEKDAVRISTPADPGYY
GTRDEFESEKDQEIAELKTDVHNARVFAAICTTFAVINSCLLLWVIHNV
>RB16ORF184c hypothetical protein
MKIVDFNTLSDMGLIWKINKEILHPLGLALTRNPETGLSVGAIVSDDGNWEYPETSDFQN
IAKLNKVYAMQAEGNLLDFLLQHVKE
>RB16ORF185c hypothetical protein
MSNPNTFQLCQMILVATATRAAEPIEYTSWGTEFAISNIRDLPGRLMKSPNFFPVDPNDL
TREEMENLGFRKWSSESDLMLIPLYLLPYLKEGITVIDISDEQYYFFREEADNDHRMGLL
AFGVVPKA
>nudE_RB16 Nudix hydrolase
MERSAGILFLNNGSVLMGHATETPHWDIPKGHIEKGESPINAAIRECFEETGVVVEQHEL
LSLGLIDYTSKKELVLFVYVGNNYPEAEKCVCASTFVKNGRTITEMDDFKYVPYSQIRDH
ARKTMGHLLTKLVGSIS
>RB16ORF187c hypothetical protein
MTSTAIQQNNHDVQLAQLIKEHNAFAASRVNEESEHTRRNLWTAIYREVFTERSNNKHTQ
AVDAADKALAAYDRKFGAQ
>RB16ORF188c hypothetical protein
MEKVNKVSLMQFDKKLGFAFSHGFAPDAETMFKMAFGIDPATLDQEVLSDINKTGTLYYA
RLPNPENGIQYQSTLEKLKTELKEIGEL
>RB16ORF189c hypothetical protein
MKIIDLVKAANALVTSDHYVDYCEQYPVPLERAIAQSGYDGVSTVTVENLKTFIVFANTF
WMYLPDNIGIRQPTFFTLCMFCETYLPECDDYEEHYGKSE
>RB16ORF191c hypothetical protein
MRSNIPSNVFTVIKPNELRIADIEAFVIHFDHSTTLGQLYSAIKSKYPYKCPKCDGKGYS
VKTFNTYPSGLPDSGWVDQMEDFKIVCDVCDGQGYTKDHLIAKPVKVEYVKA
>RB16ORF192c hypothetical protein
MRNLLNIAEIFCYGVAVYVLFHGDGAGYWIMFGGGLFLSFIKKFFK
>RB16ORF194c hypothetical protein
MKLYWLVFSNGFVMKGSVHCAKAYCEWNKCSFRVLSVASSQPMGDY
>RB16ORF195c hypothetical protein
MIPEYEANINTRNAINVNYVPPKIKFEYDGYRRVMSRLDCLIASPDCPPQLRMLKNI
>57B_RB16 unknown funct.
MKSFIEVAKPVVDSGIYMCAKFDQASCEALAQVQKLLGVENPVSAEKLHTTIVYSRKTVD
LFPASGISEPARLVDVEKWDTKYGNTIVGVLESDYLHSRFNDAMDAGATYDFDNYKPHVT
LAYDSRIEDISGVKRLLTLPVDLTIIKEDAESLDLDKTVEDITEHIEHRGESS
>RB16ORF197c hypothetical protein
MTEQTQNQTQQLQNDVLILKARVFDLNEIIQGKDQELQSHRQLVGQICGLLEIDGSQGVT
PDALLGAIKALLPEADETDDAETKDA
>1_RB16 dNMP kinase, essential
MIYGICGKKRTGKDTVSQFVLDNYQNVEAIALADEIKSILRNGMSASGNRYLRELSKTNP
FYSGDREAPLLMSNECARMVFANGIESLTKRGYWLNNADIIAYEICQTNKHPWTIRRLMQ
VFGTDIVCNENDSVWTDIVLKKILKSDKDHFIITDVRQKHEYKYLSKFGTKFVFIERDTG
EDDSHSTEKGLKPQPTDIIILNNGTLGELKTNVLNVFNF
>3_RB16 Head-proximal tip of tail tube, essential
MNTTAMILNQISPTNFMLDIPDNDYMKGLKLQIQGVTLPSVNIPITEVPLNPMIRGKIPG
SAMEFDPLTIRFAVDEELRSYLGVYLWMLGTCDFNTFDSIRWSEPQQAMALHILDNSQSK
TVATFRFYGAWPSNLGELELMYTNDSDEAVSCMAMFNFAHMEIEIDGKVLVPTPRKKES
>RB16p183nc_RB16 not conserved in RB43 ; hypothetical protein
MKSFKELLSESVQTKKFAKTVDLVDRGNASKGQIGFLHFAHGADYDVYAPDSHDLAYFGK
GVVRLKGKTTGKTQAAYVDWAKGTVSFYSGDPADDLKFDKPAKFKGASLYKEAEENLDLY
NQLAEDFEIDVPMDEALVKGKVYKLPSNDMRLLYTGRTKNKPTGEYAVFTVVDASGKPRL
VSGKRFTQEYKGDMLSKLVLAESEDLNEAAKGIREKVIAVLVKRGFNEKDAEKMVDKNLK
DAMKVRPGATPGKLAEIVSTL
>2_RB16 protects DNA ends
MSFIFEFEIIAEEDKPKPPPKRKLGEWVELGVKFRRAKLKGMTAKKFADENGIAYATFTK
SMHRYKQQIDDEISRRTAETEARRKRNDYRKKHTVDIINDFRNSLRKITVGVSAAKRQKD
STDWFGDFIKTSIKTHRVAKPATGRLYTFVYDAKYKDTLPYWDRFPLIIFLGSGRSKAGN
LVLYGLNLHYAPPKARQEFLEELLKRGYGSTDRLSNKTRLKINWNNVKGMRGADQMIKAY
LPAHLRSPLAEIAPKDWAKAVWLPTQAFQSKGKPYSAKKVWNRY
>mobE_RB16 Mobile endonuc.
MKYLVYQIKNNINDKIYIGAHATTDVNDSYMGSGKLLLKAQTKYGIHNFTKSILYVFDTP
SEMYDKEKELVNREFVLSEHTYNLKIGGEGGVSYTTASSETREKMSKAKIGKSRKMKDGW
VNPLKGKTRPGLFNEQSIEKMRNAKVGRSLSEEHKQKISISCSGKTMPPDAVKKSADARK
GKPRTEEQKIRIREAVSNIEKMECQYCGNSFRPGMFKRWHGDKCKRREL
>4_RB16 Head completion, essential
MPQNITKYKGDPRKITYRSSWEKYIMNWLDRNPHVKRWNSEEVVIPYFSNADGKRRRYFM
DFYVEMDNGVTYLWEVKPMKETLPPPKPANNNVHNKKKFVDALYVYSINIDKWKAANAAC
KAKGWEFKIITEDTLKRVFGWKGYEK
>53_RB16 Base plate wedge comp., essential
MLFSFFPPVDYKGTPTTDIFRDYRFYFNRVIRNYKPRTYQLTGSLRPEQLAETLYGNQQY
YWVILMLNDNYDPFYGWITDQETAYQCAVQRYSKVGGEQVLYHMDGKNNRYYNLVEDPNN
PGHWYDKGDKDMRYLQYQGTLVPIDIYEDAVLKNESMRTIKIINPSDIQSFVSDYIKEME
KANL
>5_RB16 Base plate lysozyme; hub comp., essential
MKFGGNMHSPFFEGVVENVDDPRLLGRVQVRVFGEHPAQKQKSETIGIPVEELPWMMPIQ
DIRSAAISGVGFSPTGITRGSFVIGYWRDKWHQDGVILGTFAGEYREKPDTQKGFCDPFG
EYPRYVGNDVNVLARGGAEGRGSSSVIIRDANSSLAVNPDDRPLDEIPEDNRPDTGGFTI
EKMIRGDEGIRLTWYYDVKGYTIGIGHFFLTAPQGTDPAVVNAALSRQIGRTVTGVPGSI
TADEASVLFQQDLAKVHNDIQNNSKVREVYVTLNRPRQMAIENMCFQMGVGGVAKFTNAL
AAMKRQDWKTAYNELRNSTWANQTPGRSSRVSKIVLTGNLESYGVQVPDPEGRSLSAAYN
AVVLQTSNPEDPFVPGDTRVMFEEPKSAYAAEYPYNMVFESRSGHIQEFDDTPGFERYNR
VHPAGSYEEIRPDGTRVVKIVGDDYLIVQQGRKVNIKGNLQVVIEGDAFIYNMGNVQQTV
DGNVTEFVRGNVNQTVEGEYVGRIKGNAELTVEKDATVNVDQNLMANVKQNATVNVTEDA
TVTAKNAMMDIEQDFDLNANNITMVARQNTLIDSGSLTKITGGTVQVG
>RB16ORF205w hypothetical protein
MIMDYESIIDGIMQDFQHPCDAEIPAGSYRRIIWQGHTEDYPAVGVEWDTEIIPIGAHLY
TQSPFGQKSDPLPVVNSPGTDPGTGEATGILVEKIGYYFATQQEIDDYITSIGATKLTGN
DWYGADLTKANLYKNPGELAMYKVENSGGYLLTSGPRCDQRIRQAYNEDTGAFTSIDYYW
NGNRIAYMKHDDTGAHNCKYVGMVVNTNADTSIPPVPPAMPSIYGALPSEISMMRSGLGC
LPATVGFAYTNISDAMLSAWNETRKSFKLVFDMLTGITKTGSGGISTMYDGLSIAMEEIT
AGALALSQQAWQAAIKVFKDIMSSALNIVGGAWNMIKSFLPTVTILGVSINIYDLIFGDN
SVQTLKDSFQAIIDAGTETYENVINAIYSAIGSAYNYTVEYVKAGARDLVDACSTLFDWC
ITMFQNGCVALVDLYGRIMQIWAMPPTVPNPLWAAVLAIRNIMMQIKPLDVILGGNFPGF
TAMDLYQMAQEKVKEFIDQSYAQIRVYYDQVKDLYNTLTTQTQERDAIKRKFDQYLNWMW
EPVKEATTAAYQAALDAANAAVNATKAAYEGIKAQIANLQNGMKDTYSMAMAELKKLPVM
AQINQFLGYCGVAFDDLLKTYENALTGAQSLYKNFVDSSRSFKDTCKVIYNQICTLALSK
VTQYVNKLLSLIGLAITFGSISVCVPMVQY
>mobE_RB16 Mobile endonuc.
MNYDRIYKALIDKRRKTPLKDGYKEHHHIIPKSMGGSDDFDNMVYLTAREHFVAHLLLAR
IHGGKMWFAVAMMCGRGSSSAKGVVPTSRIYELAKKRVANERSILFSGKLHPLYGKPCTE
QRRKRIAEGRKGKTHTQETKQKMSESKKGYKHTQETKQKMSESRKRQTPPTLGKKLPSPS
IEKRKKLSEAIKNQPIIKCPYCGLESNSKGNMVRFHFDNCKYRKP
>6_RB16 Base plate wedge comp., essential
MATTRKQINQIPDIFVGATFDEIKSDLINWLRGQDEFKDYDFSGSRMNVLVDLLSYCTLY
IQQMSNTALFESFIRTAALRSSVVQQAQDLGYMPDSRTAANTAILITAKNPLNPTSIRIP
RGTKFIGTVKETNSFPFVVSDDVVIVRDKDNNYVSMLNIVQGRLVRTEVIFDGSTILIRD
PNIDRSQVRVTVNGAQWDDWTNESIVNATGASTIFYMRETVDGHTEVYFGEGETSQQVAG
GALTADYIGGLKPANGSTVVIEYISTNGEEANGAENFVYVDTLTNISITNIVENPTDSAD
YVGADGGGEPEDIERIRELAPIMRETQRRCVTASDYESFLSHRFGSVIQAVQCFTDKEKP
GYAFIAVKPKSGLRLTSVQKEDMQNYLAKYNLATITPSILDPNYLYIVQSVKVTYDISKL
IESEEWLRGQVINEIDRYYTDNVEIFNKSFSKSKMLTYVDNADVSIIGSSATIQLLRELD
NYYSAPMSGIHFLNQVKSRSVVSNGFKYTNAAGDSYDVRYASTDMNTTTGLAKMVIGPFK
NGDIGIAAYTGNDFDKYPGVTDRDKYYEVGYVEHFNDFISFDLGVLNVPSERFSAAYIEL
TGTPLEENIFTRDGSLIVFENDLRPQYTTLTMNPISQ
>7_RB16 Base plate wedge comp., essential
MIKAPSITSLRVDKLAANFVYLKWDSVGMDFYYVVEMAETRGAGGAVIPDADLTWFQLGY
AYVNEWFSTAVQPDSFYKFRIKVTHQGFEPSDWVYSDELWTFTLNAYAYSTMREFTPSDA
FINEKFAKNNQNYVNFNTDVVMAALMKEDFVFSPLYTDVSQISDKILTQENYHEIQDHIE
HVCNDINRTFLVASNGLLYLFERFQNMAKVSNDKGQTWHYYKAFNDRVGNPVSRSVAYQS
TNTTYVLGYDRIFYGRTSTDIRWSADDVRFSADDIIFAKLGNQTGLDFDVDSYNTFAKLP
GDVSKYAEAMACSDDWLYVAAKNIVRRIALKQTPIDTDPSSPTFGEKIFDETSYTIVPGN
DKIVVKKMDVMDSKLYVLVTGEVKVALQDPTKPENVVPSVDSGVYQWQEDTKTFVRLYGN
TEEERFFIEHEYTNMSTNGKEIYISVANYKYPGTLPDPELLITNPELVAAVKYDLRPGYT
ASLSINFATIRANIDDPTVWKFGAQEYYNEANYSWFFRDSVRTWITNDNRPLVVYPKIVY
EMVTDTAGPSSTLRVNKEVWDRGHVTIYINNIKFTGFTKYTNGVLLYKSSGEIIGFFELS
YRARDSLTIFWKPDNTLLIADLIQQEREQPYVPDLSPGLIDPDLSHMITRFAPQSYLDQE
YFEKFGEYYLQFVSLGENTYYNKLLNLIRNKYPREKNCVEYLWSEVNRRNIYLDKTKRDQ
VVRFFESRASDFYSTKGIEASYKFLFKLLYNEDVSVEIESSNTLEYDILVSSTNISQDIV
GRTIYTPTARANVTYIERDYEDGQLRWSMTLHNVIGNFLEGQVVKSEKTNFTGSILRGVR
GKQMANNSIDYFNRGRSYYVMKIRSNLPASRYKDDVLRFVHPVGFGFIGITMLTVFINSG
LSMTHSETIIDILRNYRFDSGYPKYWPDRVARLDGNGNQTFDLVTGEALYEPHPKAGQPF
DVPPQYDIDEQPLNGVLPSARRFDQSPLFDSSAVKYSQFRNLVEKRLKDDAGNPRDPNPP
TQRKVGK
>8_RB16 Base plate wedge comp., essential
MAQQNIYRAVVTGKFRTENMMNFRDMIGDDPDHNSIYMSIGRTEQWADNESDPEFAPPYP
NDDTDGIVDMWTHMIGATKVPGEMIDAIVPRKDWGDTRYPNPKIFYVNDIVVVNSAPYNR
TDYGKGWMIYRVVDVPDIGSCSISSITGKVECVRIGGIWTPTHESVEPPRGEANGIDMGD
GYKWEYLYTIPPDVVINRCTNEHIVVPFPDELEEDPVRWGYDNVIKWYPDMYDLVFRMKV
HSMRFRAYMDSLFFPQASLPGNRGFRQISVIVNPLLKKAQPTDPEVKATGQFYTKDQFEL
DSGQMIYMENRQPIIRSPDQTEEVSIIFEF
>9_RB16 Bp wedge comp. tl fib sckt, sheath contrac, essential
MAYQTGKKLIDVGQIGNPSTGDPLYDGGVKLNEIITNVYNAFGDVRLLTANDGVGTMLLH
ATGYFQKLPRTYYSANPIELGSLHDMDTATGPITVVLPSGKAGEGCYFINSNGSISVDRP
VVFRPQVGDNIKGVQDQLYITSPYTQIKLWCVKKEGSVTTWDYSVESMFGSKTMPVDTTK
LILKASPTAIPLFGYSEFSGAKLLVYAENMTGTVNKMAELLLSVDRIARGVYSTEYAVLK
NSDDDMYSLTFTVGAGDIVYANVQSVLEDRIKFSIKAVDTIKSGIAA
>10_RB16 Base plate wedge comp., tail pin, essential
MKQEIIIGNVVDDGAGDYLRRGGQKTNANFTELYEKLGDGEIPHPAGAWKTHSAPTLNPI
FGDSWALNTSNNRITVNLPKGGVGDYNKVIRLRDVWSKWAVNNVRIVPATGDTIKGSPTY
KELYKDFMDVELVYCAPGRWEYVENKQVDKITTSDLATVAKETYIATQGQTDFPNVFGPG
NSYNVRALEVYYRGNLLYIDDKNGFVEANSDYGSPGTNPGELIDLDGTNIRLKRPCNAGD
TLQFVTYMDGIATWRSTYEAHTMRVYNTGDTELVSVPGEIWVGNLATKKEFTTAEFGISS
RVLINPNSFELLLNGRQLVKAGDADLPTFVCEGAEGYDEDSCLANSGAWVPSGQDYSLIF
VDSIVTGIKFSQPLESRDVVTIRWFNNDIGTVMEWEGVGGIKEHTDKIYLNNEEELTLVG
RIEYTDYNNPSQKTMRKITEPFSGRLLDLQAFFDVIHPIGTIYENAHNDANPGEYMGFGI
WKRYAEGQFIAGWTTDAADSDFGLNNNDLDGSGQPTHTAGGSGGERGYEIHPINVPQIES
TDKVLIKDDNGIIIIGGCQVDPDATGPGYTKYREDVLKVNQGNTTPDKLKTLPPYITAHR
WIRVA
>11_RB16 Bp wedge comp. tail pin, binds sh tail fib, gp12, essential
MTQFISKTREGAKVPSREADFLQYEMGTKDPLIGGKRTIGGANVDQLRKGVDYPNVQSAI
DDLYTLSQQIPINGVIMMTEDSPPTAVQQVETITFDGTVQNTDPDQTKATIHVYGFPFVF
DNTTNASTVCETVYNKFTEFVNDEKYFDLVTRKGLNGEILEVRFIDCVPHPVTNTTENGI
SMVGTIDVQARSGYGTWSKLGEVDLAVTPAVPIFYFKRIA
>12_RB16 Short tail fibers, essential
MSNNTINHVSDASVYVTFDPAGTQWPSTFVNVQQALASIGPWARTDVGLPNAAPGMRGIA
AIATEAMIDAGTDNETIVTPALLAYRLQNPHASQTVWGYTKYATDAEAVDVANDLVSLTP
RSINVVFNTRHASETVWGSSKLSTTAQATAGTDDTTSMTPLKVKQAISALVPVQSNATES
AFGLVQLATVSEVRAGTIRDGFAISPYTFIRLNATESDLGIVRLASQAEVNAGTDDTKAV
TPLKLANLKGSGGSFGLVKLSTEVNAGLANTALSAGANVVPSNRDSAITGGALYQGSVAA
ANKYQTHSDIEASLPIGCMMMAAFNSDYGNLCIANGRGMYTYEYPELFARIGYTYGGSGN
IFNLPDMRGVVARGFDAGRGLDPGRGFGTYQHHEVQSHEHPLQMIYQSGGNLPSWQCVYE
LRTAEKNDQKLYWPDPSLSKAMAVGGNETRMKNLAVNYVIRVR
>wac_RB16 Whiskers, facilitate long tail fiber attach
MISKLNPLPKIPFVDGVPSDTTQTPINWIINGETLDGAKTKVTNEGSLNRCGVLVQKNAV
QLETNTITQTAKINEVIDQVNLISENLAAISDESVIDKLDQVVADVEVLKVDMTAVQGST
ASNTLKIQDLDKEIGTWDASTDPKHRTIRKDIIFLKGEMGAYPGFNENGDVDPTSTGSGM
KYKIMTNAQAISIHEGRITRLEDDWANSDVGHLTDEVTDLRNEMGPKHLATFESVYVRLN
IIGTEITGINSELTSINQYIGRTGTGGTGSISARMTTAESNIATLQTQMNDSATGVLPRV
ISLENAVGNSQIPGSIRYDISAIKRDIGDINMIVGESSDDGLRGEMAQVMTDIGTDSQPT
SIKGRLLNVENTQRDDHQKLIDVESVVGNTSSGLVAANIAMGKAVYGDATSSDPFLKDGI
QKTARDSKAAIGVNTTGSETGIYKLISDLTARVAALESGTGGELEQRVSDLETNKASHQD
VANALVPYITEAEADVKYEPKKIPLSFTQNLVRRGDYIEGDDISFMVTVTGGKLPYVYQW
KKGTADVGTNASSILIQSITSADAGVYKVVVTDADNTVITSDEVTVAVYPVPQFDTNLAD
KSVVDGDPLTLEVVYSGGKPPYTYEWFKDNSVISGETSATFTKSAVTSADAGEYYVSVTD
AMNNQNDSVKATVTVTPRPALAFTTDLSATKSYSTGANMDLAVVVTGGKTPYTYKWFKDT
AEISGQTGASLTTVAEDGVYKVEVTDALTTKITSTECTVTVA
>13_RB16 Head completion, essential
MITNNPEQLKDEILRRLGAPIIKIEITQDQIYDCIQRALDLYAEYHYNGTNKSYIILTLG
EDNPRNVFDLSKEHIFAVTKVLRTNIGSLVSMDGTAVYPWFTDFLMGLTGGSLGGRCASS
VYGMNAYGADLGYFTQMMSYQRSMQELLAPLPDYWYNDDTGQFCVWGKVNNGDIIVIEVM
VRSFVDVPSAVGSVAGYATAGSNAVEDQSIADIYDNPYNAVVGGVRAGQGTTVTGGTSAY
NNRWVKDYSTALVKEINGQILAKFQGMQLPGGVAPDGTRLIQEAETKLQGLRDELISMSD
AVPIIMV
>14_RB16 Head completion, essential
MQNWDESLFAQLSTGEGVDRNLKDQVTNPYVNWYKYNPTQQLHDSLTAESIQMKSPDMYY
VRREFVNIDKILGEDRESKFTKSWKIAAYIESYANYEGQRDFFRKFGLSSNDEMTLVLNP
RLFAHQTDGGIPVLGDLVYFPMDNSLFEITWVEADPFYQFGDRPQRKINLAKFIYTGEEL
APELQRNEGIHIEPDAELDLEPIRNLDGLADINIEQYEEDKEFEREGDEFIESFDVVNGR
GSPFASLP
>RB16p201nc_RB16 not conserved in RB43 ; hypothetical protein
MVAKISIEQREHQLKERCAELELSFDGWVDQSAITKYSKFYVVCSKGHRTEKQIKPFVNK
SRPNGCYLCSPKMKISKENRIEEIKTLADSIGYTFIDFVGVYKDAHTKISMVCDKGHNWD
VSIVAFLNQGHRCKKCATSGFNTNKPAYVYVQSLSGKFLKFGITNRTPKKRMCAQSNKSV
YKHELVYQKLFDKGIDAMSIEQKIKQSLVCGVVDKSDMMDGYTETTDISNYDKLLNIIEG
V
>15_RB16 Prox. tail sheath stabil, binds gp3, gp19, essential
MFGYWYNSSLRNYIVLMGQLFNHVQVKRVRGDQEKFIKVPITYASKEKFLASMNKLNYAY
SQENVAKTETILPRMNLSLVDLQYNAIRKTSIAVNQKMTQLQSPRKTITQFNPVPYRLIF
ELGVYTRYEDDMFQIAEQILPYFQPHFNCKITELHKNEITVDRDIKISLQSVAPDTTFEG
EASQRRHVEWSFMFELQGYLYPPVTDVKGEIRTVYTDFFANMNPLDKDNFESVDSQADPV
DLPLQDYTGEEYIQTYSHDKPIPSGDEPPKPRE
>16_RB16 Terminase sub, binds dsDNA; Truncated C-term.
MDDKLNLQELLNIDALPGGVESGEDVVVYEKLELKPVESHPADRKPDLEEDYSLARTTAH
YMNQMIMDMAEIALHNAKNSESPRHVEVFTSLMNQLNVSNIGLMKIHKEMREITEEKTTT
SSKESKGGEMNIENATVFVGSPTELMQKYGSAYEPKEGFIDGEVVEVNNDGNGTDDRSE
>17_RB16 Terminase sub. nuc. and ATPase; binds ssDNA, gp16 and gp20, essential
MEMEPTIDPSKESDHPIGLMNPQYLKRKIDEAGMEWIQSQHDNKWYPYTFSDYLKVNAIH
KVDLQSTDRTKFATYKDKTNKRGRYNGNPNLKRAFVQTKWTQQMLIEWVKCRDDIVYFAE
TYCAITHIDYGTIKVQLRDYQKEMLIEMHKNRMVACNLSRQLGKTTVVAIFLAHFVCFNE
DKFVGVLAHKASMSAEVLDRTKQAIELLPDFLQPGIVEWNKGSIELDNKCKIGAFASSPD
AVRGNAFAMIYIDECAFIPNFQDAWLAIQPVISSGRKSKILITTTPNGLNHFYDIWNAAV
EGKSGFVPYTAIWTSVKERLYTDGDDGVFDDGYSWSAKMIAGSSKEAFLQEHCAEFMGTN
GTLISGWKLSKMSWIDIDETETNFYQYKKPIEGHKYVAVLDPAEGRGQDYHAMHIIDISA
MPFEQVAVYHSNRTSHLILPDILLRYLNMYNEAWIYIELNSTGHSVAKSLFSELEYENVI
CDSYNDLGMKQTKRSKAMGCSTLKDLIEKDKLIINNKKTILEFRTFSEKGVSWAAEEGFH
DDLVMSLACFGWLTTQMKFAEFCEKDDLRLANEVFAREREQLYEDALCPVIVTSGDETIS
VGSHGISFI
>18_RB16 Tail sheath monomer, essential
MALQSPGIETKETSVQSTVVRNSTGRAAIVGKFSWGPAYQIRQISNEVELVNYFGSPDNL
TADYFMSAVNFLQYGNDLRVVRVVDKDAAKNASAIFNQIKTTIASQGSNYTVGDVIKVKY
SNNVVEENGKVSKVDSNGKILAVVIPSEKIVARAKQIGTYPDISTGWTTEIVSQSSGVSA
SITIDGIESDSGITLLNLDIAKETIQGTAFQTLTQKYQIPSVVALYPGELGSTVQVEIIS
KAAYDSGAMISGFPSGISVKNSGRSVMTYGPQTENQYAFVVRRGGIVQESFIVSTEKTDK
DIYGVNIYMDDFFANGGSQYVFGTSMNWPKGFSGILEFGGGLSSNDTVGADELMTGWDMF
ADREALHVPLLIAGACAGETVEVMSTVQKHVISIGDERQDCTVFVSPPRSLLVNIPLAQA
VDNIIEWRMGYTISGNTPVDNNLNVSSSYGFLDGNYKYQYDKYNDVNRWVPLAGDIAGLC
VYTDSVAQPWMSPAGYNRGQIRNCIKLAIEPRTAHRDAMYQVQINPVTGFAGGSGFVLFG
DKTLTNVPSPFDRINVRRLFNMIKKDIGDNAKYKLFENNDDFTRASFRMDTGQYMTNIRA
LGGCYDYRVICDITNNTPDVIDRNEFVATVYVKPPRSINYITLNFVATSTGADFDELVGP
QAV
>19_RB16 Tail tube monomer, essential
MLTDILRAFESGDFARPNLFEVEIPYLGKNFKFKCKAATMPAATVEKVPVGYQNRKINLA
GDRTYDDWTITIYNDDAHNTRNALVAWSNMLHGMGDQISGDIPANYKKTATVKQKNRNEE
ITADHTIHGLFPTNVGEVTLDWDSNNEVSTFECTFALDWWE
>20_RB16 Portal vertex of the head, essential
MNFLGFGNVLSFFKNFAREDEIELEQQLKNDTGSVAPPKNNDGAYEIETDLNNQKYAGVF
QQFYSGQDPAIQNKEQLINTYRGIMSYPEVENAVSEIIDDAIVNEQGKDIITLDLAKTNF
SKAIQDKIVEEFDNVLNIYDFDNMGARLFRDWYVDSRIYFHKIMHKDETKGIRELRQLDP
RCMELIRESITETLDGGVKVFRGYREFFVYSAPKAGYTYNGQIYQANQKIKIPRSAIVYA
HSGLEDCSNNIIGYLHRAVKPANQLRLLEDAMVIYRITRAPERRVFYIDVGQMGGNKATQ
YVNNIAQGLKNRVVYDARTGTVKNQQNNLSMTEDYWLMRRDGKAITEVSTLPGGQNFSDM
DDIKWFNRKLYEALRVPLSRMPRDDGGMQIGGGGEITRDELKFNKFIRTLQIQFSPVLSD
PLKTNLIAKKVITEDEWDENVSKISFIFQQDSYYAEVKDIEIMERRLTLMSQVEGVVGKY
VSHKYIMKEILRMSDEDIDEQAKLIEEESKEERFKNPEAEEENF
>67_RB16 Prohead core; precursor to internal pep, essential
MKEFIEAIKSGDLVEAKKQFYSIMEDRTEALRQEMRVEIAEAVRIEGETDEDDSDDDKDD
KDGEKGEKDKKPSEKDDKADE
>68_RB16 Prohead core, essential
MQLELEDISTELIEPHLTEAKARVDILGIDEGTIKIIENLAVDEPHLALAMMSIVEGLSL
DEVIVKHVDSRGNVERKKDRKTRERNAYQTTGLTKSQRRQIARRAMKTKRANPSITTRAQ
RKRKKALRKRAALGL
>21_RB16 Prohead core and protease, essential
MNESQLNENGDMLLIEEWGLPCADISDSILESVGASKDGKLRIEGIFLQAEKVNHNKRLY
PKKVLEEAVNDYIRTQVNTRQALGEMNHPPRPNVDPRNACILIEKMWWKGNDVWGRAVVV
EGDNADGDKLAALIRAGWVPGVSSRGLGKLADSGKGYGIVQEGFKLAVGVDVVWGPSAPD
AYVKPITESQQTKPLVENISADDAFRKLSERLKGL
>22_RB16 Prohead core ; precursor to internal pep, essential
MLKEQLLAEAQNLDTPVELDSIFESVELSDEVKANFTTVFEQAVKANAVKLAESHINQIA
ERSDELVEAQVAEKAGAIETQLYEDANKYFDHIAQEWLSENKEAVSRDIKADLFESLVAG
MKELFVDHNVIIPEAQVDVVAELEDELTENQQEVKRLFEANQAQAKEIANMKRDTIVSEK
TKDLTESQVEKVQNLIEGLEYSDKFESKLTAIVEMVATKAEKQVDESTNTQTTTKDDFVP
VNENAPAEKSKINKYVEAAKRLS
>23_RB16 Precursor of major head sub
MSKKNELMEKWNDLLESQEGLPDIATKSKKQLVAAILEAQEKDAETDPVYRDEKIVESFG
GFLAEAEIAGDHNYDPTNIASGKSSGAITNIGPAVIGMVRRAIPNLIAFDICGVQPMTGP
TGQVFALRAVYGKDPLAGGTPADVREAFHPMFAPDTMYSGEGAHTAFSKITTGTAIATGA
IVYHIFQETGIAYFQNVTSGNVTVTGADPAALDAAVIAENEKGTLAEISVGMATSVAELQ
ENFNGSSSNPWNEMAFRIDKQVIEARSRQLKAQYSVELAQDLRAVHGMDADAELSAILAT
EIMLEINREIVDLINYTAQVGKSGFTQTVGSKAGSFDFQDPVDIRGARWAGESYKALLIQ
IDKEANEIARQTGRGAGNFIIASRNVVSALARIDSGITPASQGLQKTLNVDTTKAVFAGV
LGGTYKVYIDQYARQDYFTVGFKGDNEMDAGIYYAPYVALTPLRGSDPKNFQPVMGFKTR
YGIGINPFANSRSQAPADRITSGMISKEMCGKNAYFRKVWVKGL
>RB16p213nc_RB16 not conserved in RB43 ; hypothetical protein
MKHIIYKITNTINNKIYVGAHSTEDINDSYMGSGIAIKKAQKKYGMEHFTKEILHVFDTR
EEMYEKEREIVDIEFINRPDTYNAGIGGKGAPMALIGWSDEQRKLISENTSKAMQTPEMR
ERLSKIKTGKKQSEESNRKRSETIKAMYKGSAFDRTGSKLTDAHKAKISRSVSIDGVVYA
SGSDASKALGLSRSGLDYRLKSDKFPEWKFVA
>24_RB16 Precursor of head vertex sub
MSDKHYTIHKLMRQSALPSGKREKVINEATGTTDINVQNTRPELVSLTRAVNNLIYHELV
AVQETDLPVATLFGVRYRNPNGDMTFSSAATYSGRISGRTDIDDIDLAKAYVKGDLFKHD
VTDVVYEVIEPVKLNALDTDKDTAIMKAVFQSKIRLVSEAADTSKYETSEDIASTSFQMD
RWNIPVRSRKFKTEMTVELMQDLEANQFEADGVIEDILGTVASEEVNKDIIQTLITVSKR
YNVDGVVVDGIFDGTTTYTAKDAPALGRILYQLACEMGQEMNRTTSFDATYVLASARVVG
VLAASGWMTETDEQHPLATGKLQNGYYVYTDTNTPFDYLLTGCKYDLGDMDHVGSLFFTP
YTEADDAGSIKVSVDPASLQPKVAILMRYGLSVNPYTTESDSERLTKGDDWSNLAGKSKL
SQIVGIKLPKLG
>uvsY_RB16 ssDNA bind, rec. repair; helps uvsX, inhib. endoVII
MAELKLEDLQAELEKDMLIDPLKLQSESADIPKIWSKWLRYHSNAKKKLIQLQARKEAEV
KERLLYYTGRHETEMTDVIYTGSGEIKIAINGDPKIVEVNKLIQYFELIAEFTSKALDIV
KNKGYSIKNMLEIRKLESGA
>uvsY.-2_RB16 unknown funct.
MSEQEDCKCVVCKNPIPTATGFVTESGRVCGVICAQYLIERNKTGLNEADDLNEVQMLL
>uvsW.1_RB16 conserved hypothetical protein
MKSFTEFVNEAAIDDFMNKVASCRTLDGLKELEKYYNTRVKEVEVAASDDISMRDAIKGR
REELKAELETGEEEKF
>uvsW_RB16 RNA-DNA- and DNA-helicase; DNAdep. ATPase
MDIEVKFLNTSHVQIQAEANIVYELRDYFSFQPPGYQYQAKYKYGGWNGYIYLMDYNGKL
PYGLAYLVTKFAESRGYSIWVDPKIHETEDITQEDFDKWVNEHPVYDGDKQIDPYWYQRE
SVFHGIKNRRGVLNLPTSAGKSLIQGLISRWCLEHYSGKVLIIVPTTALVDQMIEDIANY
RLFPKSAMLGIRSGTAKNSNALIYVSTWQSAVKMPAEWFQQFMCLMVDECHLSTGLSIKK
IIDTMDQCIFKLGLSGSLKEGKTNMMQYIGAFGKVFKPVDTRRLMDDGQVTNLKINTIFL
RYKEEEIKKLKGADYQTEIKYVTSHTRRNAWILKLALKLAREKNENTFVMFRYKEHGKWL
YEKLSKVYDNVVLINGDTDIDDRNEMKKIAESTKGLIVIGSIGVLSTGISIKNLHHIIFA
HPCKSAVVVKQSIGRVLRKHGSKALATVWDIVDNLATLAKSKTAKK
>inh_RB16 Minor capsid pro. inhib. of 21 protease
MKIDYELVEGFRALPTKEQKGALADYAQSTFEVKLNKQKSFDNMLADLEAAVPAEEKPEL
LIDSPEPEIVSYTGSSMMDEPVVNAPNIPDVVVDVSQDFMNYVKEVAPEVADQIQLVPDV
VEAPVTASDESKADTAWLDGFSPTIVLMGRSARSNGYYTCPWWIYDWIKKNPDWYKDPDQ
CPHYSARDTLKSLVYYIKRDGQVTVRETRNSSFDTFKF
>RB16ORF235w hypothetical protein
MKNEMMKNAYYPVLFVWGGEKVKTIVNSQAPYYTVGEALRHAAEADYPVSFEPGYARWNG
SKWVADSWDNYEESRMEHDPDYVSRQMEAHMIADRRLDNEARGFW
>RB16ORF236w hypothetical protein
MNKLNHECLKDLSDGKEIENVIFLDIDGVLNNMRSMKFGEHMDIECARHLRRIVNHANCD
IVVSSTWRMGNTTHTLREILYPWGLYRVIGRTCSNMVGNRVRGDEIKAWIDTFGCKNYMI
LDDDCDMLPEQKDHFVRTDPEIGLTEEQSTFAIRNIFGVTTPFCPECNGYGRVNQYDKCG
SCNGKILRL
>hoc_RB16 Large outer capsid
MATEKWTTVHPIPWRNTSFTYLPWWIYDIIVAANTAGGDWRDYAEEKYAKEFDTLKQAYI
DYTDVDFIESRNGYLYKLSDFTPADPVVTITPKTAPADFKVGDPDLAATDLFTIDPSGTA
MTLTVDSSGHASIVGGKLHAVSAGDVVVTATSGSVTANLTVNVKVAP
>RB16ORF239w hypothetical protein
MLLFEFNDVFSKFSDAIQAKFGKRPENMTETEYNTAVSSLVRTDFYEKLAIEVLGWDMMK
WGMTYRDREVGFILVNEVKSPLWVNNQKIAYMDKVCAEMGIVRLDFWMCKDLNELKGHAY
RCPLISRNEKHRQAWDSAGKYRSVYLNDDMNITIQDVNRAFADYTP
>RB16ORF240c hypothetical protein
MDGVLFDWEGSFIPMYGDPARMPEDELKKAKEAISKTDFYENLKPIEEGVALFCHMRTLG
EVAILTSVGKYNSEKVAEQKRKALVKLFGYLPEFHYTKSSGEKAAYASQGVLFDDRAKAV
LPFRKAGGKAILFVGSKEEALKEVRKL
>RB16ORF241c hypothetical protein
MKSFKDFVSLDEALITFGGKAYPKFGQVVILAGGAGSGKGFTLEKLLGIEGITLDVDALK
KLVMGSTKLAAEIKAKTGHDVKTMNLKNPDNVATLHHVIADVFNVSNKNQARVYAGIAAA
PEDRKPNLIFDVTLKSMSKLASIARDVETLGYHKENIHIVWVMNDVHIAMQQNLKRDRVV
PKEILMDTHEGAALTMAKILNMGDSLKQYMDGDIWISFNKVGIDSEIKKSDKGGMFVVKS
NYIKVKAKGKAQKSIDQLDKELVAKVAAYAPKTDTWG
>RB16ORF242w hypothetical protein
MKMQLNHFIKSAAAGDQSKYKSNRNHSLDKDFADFLGFKRWHTPVMRPDCDPKYDYPRWG
MSRHAVVKNIRVMSFRNLYGSCIIEIANERDIILPNGWKLADLVKTLIQIRKEYKNGYIR
SMESLGAYSGEDYREWQSVAKYLINSVFGIICSKGSAINLGGHEVIARAREKVAEAINQI
IASGGTVLHVNVDEIAYVGKQVDIPNVHHERFNNAVFTGFRGAMWGDHAIISGPVPTLRF
DMDDWEPSRHYRLSDEEQRASALRMIDSRRDRLVKELNEYMNKTKEEVLRELNVDCDSIS
L
>RB16ORF243w hypothetical protein sim to RB69ORF040c hypothetical protein
MKTIHCREEHTVYYHGSCTAAGIESMLLPPCASETLSEKGRKKNLDRVFFTADIGLARIY
AGRAARSIGGDPVLYRVVCPVDAVCMNDDKGASVYHAAWAFCEEI
>RB16ORF245w hypothetical protein
MNDRVLAILVFLLGYRVEVLGWYMALNGDLTAIWMVSLGILFTFLSCDIDNRATQ
>RB16ORF246w hypothetical protein
MKLFYVVYSGMVNVDVPLLSVETIDTLEGKIGKRFKTTVSEISTVFVDHPSDLENLINTL
DDLQIPFAEIYHHQSGLYLIVTFVLKNVDSRNPEVLDFIRNIDSNKGK
>RB16ORF247w hypothetical protein
MKIVQRNISEVSQEEKVQIHFKFNDLKRGYAEIARVHKLDNGDIYMIVQEIERIRAFRAE
NPKVKRVLRRVYVNKHRKAAKPVKPKREPRPDNKRKAINGAMALAFQEAGLV
>srd_RB16 Postulated decoy of host sigma70 or sigmaS
MSRRNMERWNTIVTSSIKPVAPAFKEVVEETPVKTQTVVSLSEDDLEHRRRANQIEFDLR
IARSYNSKNDDARSRNLQFALTLGDWTVLMSQTTCAYSGKVFSTRGDSPNSRTMERINPM
LGYTPENTIAVTKAANSEKSSLDAFMKGSVILPEVKLKLLRKAAYQIEKQLKIKG
>rnlB_RB16 2nd RNA ligase
MFVKYSSLTNHYEGKFINGVIMNGLTGGVWVAREKIHGANFSLMTSDGEKVIPAKRSGEI
LPTEQFYGCEPVVARYAPAIRKLWDALNTAQQVSGIYDAPLVIQVYGEFAGRGVQKDVDY
GEKDFYVFDIRVNGNFLPDNVVATYAVAVGLKMAPLLAYGTFDEIRALPITFDSVVNLAN
SGAIPAHNGVEPEFKNFMTLKDGEGENIAEGFVMKPVHPAFMPNGDRVAIKCKTTKFSEK
KNKQANRFNAPAELSENDKVKLDVFTCYLTENRVKNVLSKIDSANLTAKDFGRVMGLTVQ
DALEEIERNYGPFIEQFENPTLAKKTFTNEASSLIRTNWGAILNNEF
>RB16ORF250w hypothetical protein
MNFKTVLENAKTATLIGSREPPERIANIAIKIGRALSDRGILAYSGGAPGMDSHFLFDYA
PERRRIILPENGFNGLCSNGMDIIDYNELDTYKAADEARKVSGNFDYQNEWTQRRYARNA
VQILRENLDSPTDFVLFWAIEKDFCVKGGTAIATRLARLYGVPSFNLWKENVLNDVCDTL
GINIKPPTLDFLWC
>RB16ORF251w hypothetical protein
MVEINGIGVNPNAGMTISKNDPRCGRSPTLAERARKLVEETNGKMFETCREEITRNILSF
PTKQSYTFDMKRFVGTTMGQECTKRAFDMIGEWLTEEGLTYETQAGRTSVAIQYAMSSRR
ISGSTTVPERTGYSEYTYFITW
>RB16ORF253w hypothetical protein
MEIKLIPTCAGYCLALNGVANNGKGLRANVEAMLNELALRSEPGMQYEYDDVATSVKISN
LVMDGVDCAGWWDCYIDYADNRVFLLTSN
>RB16ORF254w "hypothetical protein"
MKDYISEAEALEESGFQVTIDDEEDGGYDGGVMWGLKRPQRKTPVQYSDGSVRYETVVKE
VNGRVITSERQKDIKQLYDVAKAAKVGTEIVCPVCKEKHKKTTYHKVFCSNGKKSRKDCK
SKYWNTIHPERLDRIF
>RB16ORF255w hypothetical protein similar to sp P43490 Pre-B cell enhancing factor prec
MKTFNELNSIITSTDSYKVSHWMQYPKGTDAAMFYIESRGGKFDEVVTAGVNYVARVLAE
PITMKQVELARVLYRKHFGKEIFNYEGWKKIAELGYTPVIFRAIPEGTVVPVKNAVATVY
AENEFSWLAGWLETMTIRGIWYPSSVATLSRECKKVLAHYLDMTSDLTGEAYNITLGTRL
HDFGARGATSAESAGIGGLAHLYNFIGTDTVEGMIMAISLFADYQTLFDEVENVEVAGVS
IPAREHSTTISYGKENEDEAYKNSIEMFGDGFYACVYDSWDYKAAVDRIDSYKEKIIASG
GVLVVRPDSGDMIDNIMYTLRKLGQIFGYTVNSKGYKVLHNSVRIIQGDEIHGPETINRV
LSWMEANKWSSENIAFGMGGGLLQEVTRDTQKYAEKLCAIRINGVWKGVYKCPKGSEWKK
SKKGLLMTITNGMEFKTIDSLEESIPVGWFDAMVTYYDNGYLNKTNTLGGIRERSRI
>RB16ORF256w hypothetical protein
MSVAGFNIRANDNGSVIFYNNQPLVARKGLFCKLVGYGFKLEQVDNATLKEIVRIAYLLK
DKKDEHKAVAMLEKLGENHCFIINRGYKYDTIALFEKGLSEL
>dam_RB16 DNA adenine methylase
MSLNVPKPVLSNDYDKTLIDMYERLKTLPDLSPVRELIASKGLGKDKKEEYLKFRDEYNQ
NKDPLWLYVLILHSFSNVNRTNDKGDFNAAVGKRTLNFMTEKRFEHFKKNVTGIEFRSGS
YSDIEINDNDFVYCDPPYLITDAVYNKFWNADRERELYAFLDSLHERGIWFGLSNVTHHA
GKQNDILIEWMKKYTVHNLDKKYLLGQHTESYEQNKTQEVYVCNYQKREVNTFPQTLDDL
M
>nrdC_RB16 Thioredoxin, glutaredoxin
MFKIYGYIPSVYNCAPCLNSKRLLDAKKHEYEFLSVADSKGEDGKPILNESVIDELEALT
GTRKMSMPQIFHDGKHIGGFDQLREYVRTL
>RB16p241nc_RB16 not conserved in RB43 ; hypothetical protein
MQDYGHWKTLKDVDISNYLGFVYVITFENGKKYVGAKKIWKRIKVPPSSFKRGPRKGFEE
SDWKTYTSSSKEVNDMISSGIQPKDYLIVGWYDSWGKTLLAEAEMQFSNDVLRNPEWLNK
QIGGHFNPNCFDDLTYEDIERYMHFDKGNEHTSWPVMYRVGSKTKYVNPDEVESHLQQGW
QFGRSRLEKLSVVCVVSKYKLYNTKTDEVVEVVNQNEFARQHNIESGHLTNLLKGSTDSV
GDWTLLPEVRRKNYVIEDDKGNKFSSVSECERANGLKRGAATSLCKKGIYKKMVPESRTL
YKKRLSTINYVESCRVESVSKITENSFRGLVPDLAVLHDSKESVILWLEQYISYLKAMK
>nrdD_RB16 Anaerobic ribonuc. reductase sub.
MKVEKRDGKTVDFDKEKIRIAVEKAGGTMTDADAAIMLVQYNQIRDGSAMKIARIQELVE
ESLMKTNPAVARAYIEYRHDRDIAREQKSKLFKDISGMVNLSNKEITNENANKDARVFPT
QRDLLAGIVAKHFARNHILPKHIVEAHDSGDIHYHDLDYSPFTPYTNCCLVDLKGMLENG
FKMGNADIEPPKSIGVATALMAQITAQIASHQYGGTTFANVDKVLAPYVEMTFFKHLRDA
EHYGIEHYNDYVYAIEKTEKDVFDAFQSYEYEVNTLHTANGQTPFVTITFGTGTSDYERM
IQKAILKNRIRGLGKEGITPVFPKLVMFMEKGINLDPEDQNYDIKQLALECASKRMYPDI
ISSANNRAITGSSVPVSPMGCRSFLSVWHDDNGNEILDGRNNLGVVTINLPRIAIEAEAQ
EEEDAHDAFWRILDERLDLCYDALMTRIESLRGVKASVAPILYTEGAFGVRLKPDDEILE
LFKNGRSSISLGYIGLHETLLMFGSGQHPFDRVGSQNFGKHVLEHLKNKTERWKAETGYG
FSLYSTPAESLCHRFCKLDFEKFGSIKGVTDKGWYTNSFHLDVDRKVTPFEKIDYEADYH
YIATAGHISYVEFPDMKNNLQALEKVWDYAMDKLDYFGTNLPVDKCFVCGSDDEFTPTED
GFHCKHCGNHDPAKMSVTRRTCGYLGAPAVRGFNEGKNKEMMHRTKHQN
>RB16ORF263w hypothetical protein
MMYWTKDYFEFRDEESFGTVYRNLALRGSPLSPNQLSSVVFPIKVTHCNRKGVSGIVDAN
GTTWYSEDSYLFDNEDRGFFKKFVALKPAVEKADAQQLLDCSHLLGRIYVDGKLVTKPGD
LEKFLRKARETTLKDTEKRYDTATANLQRLSGELKVLRGE
>RB16ORF269w hypothetical protein
MLINKTQCKAINFLLHELIESGIRFEFVDPINSDDRHLLRWVSGSNPLDSVSQVVESALK
HMPCRVLLGSVNASTWNGSDAYYVGFKKELTDDE
>RB16ORF270w hypothetical protein
MKIKNTATENLCNEIAVTYWKEGHVKAMKDFQQWCDTQKLANWEYAVIVERIKELILEKK
GTIK
>RB16p246nc_RB16 not conserved in RB43 ; hypothetical protein
MIQLKLDTHTLNNLFPEAKG
>nrdG_RB16 Anaerobic nucleotide reductase sub
MNFDRIYNMDMVNGKGIRVVLFVTGCNHKCEGCYNRSTWNPRNGTPYTEETENELIKLLS
NPHVDGLTLTGGDPFYRTNHPKLLKLLQRVRATFPDKDVWVWTGYTLEALQGDTERSKLL
PFIDVLIDGRYEKDLPTKKPFRGSDNQRMIEFKKNSIEIKNIA
>RB16ORF273w hypothetical protein
MILNFKTRKEARDYCWKWSIPLKNITKGSGSHPWTVRTKETRFETGKDYKLVDVEGFTDN
GKNIANSVQSKQIHQLLNGVVNIASRNGDRYTFNAPAGVAMNTLRAWEAKYFTEVAPAKA
PAPKRAKKPKPVGKPSAAPVPAKPDLDSELDGGVNLAQTIEPVAKPAAPQPATVEAMPGN
FVANRPYVLVDEAGFLRSHTANKRIVQHIKNNNGVLVFVTVDGDGDATISQDRSLPFVIH
RERKFFRELGTGTVQADTPAVQTVDIAKQQRDKEIIEAAQAVEDALAEHQKAIEVVTQKA
RAVREAAAKLALLASK
>RB16ORF274w hypothetical protein
MELFAGKTYGLTVSPEIFAEKTWKTGIANIIREKGYVTIDRTSIGEFEDRAFIMDGGYEY
ELPASLWKWFKEVTPEDGEFTPEEPEEVNLGKGVEAENVMRIATPEEVSAGVAGSDLRLM
EIPKFTYRPVQENPMRDLRIDPSFGANLETLSIAPMPVRKSDAMLRFALQHVFSGGSIYQ
INMESELNIQEDQIANLFDLHTQLTAVENIEKLLGKEKKRILQDLKPYGKKNESRNIRNP
RKSS
>nrdH_RB16 unknown funct.
MKVEIYGIPESLHNCYGCIQAQKLLTEKGIEYTFYPVLKEAKNDLGFEYDRPRIEELAKR
VRQRSLAFQYPRIFVDNKLIGGYLQLKQLIGD
>55.2_RB16 unknown funct.
MSREILLPAANAVHAETMEYMEKFVERDKTAIITPTHLDALEDRLHKQIKDQFPEKVSRN
FIRQEIVAMILKHYGVEIFGVEPLKPKKPRQMPTQITDEAIKKYQKKYAKNK
>RB16ORF277w hypothetical protein
MIFNTIECVPSSGKTKAILNHINQTGEKAIIASISMMLSKQSYDYYINQVKGKRAVIVDT
DHRTKRTNNDALREVVNDYDVIFITHAALKNIDDFDLYKDFSLYIDEVPDLVAFESLRFN
SNIKHIREICLPFSCNADDIVDLKLDEEKRELVTRLAYDGLRKRDDIAMKMFPLYRALLG
AIPVKMQCSDSGYVCYFVEDHDVSQWKFKNVTIASSNIKDTITGKILKTFHDVEFEESPL
QKLVDFKQYKNTGRIHIHVLAEGDYSRYTGDLSQSGTTVYTQIKKRVEALLGGEQFIYCT
NTYRSKFSEGQEIPYNSHGLNFYSSYTNVVALFSYNPLPWLRQMLRAVAVSSGLEEEELV
DAYVVSKYYEPAFQLCARSDIRHNNSKRKINLFVPDMRLAKYMKEKYFPDAIIETTEAVQ
TKRQRKSFQSLFQMTAQEINAFNWYKKKHKLDFADPLHHAIVKDWLNNYREKKAT
>34_RB16 Prox. tail fiber sub, essential
MVAKSFRATSGLDAAGEKVINVGKASRSVLSDGVNVDFFNEFNTIQQYDSTRGYAAFMAI
MYARRIWYARADIPSPAGAFDETKWISTRNDPKWVYNNVTSADGLPIESGTYLMADGRFS
ELTYILPDSPVEGDIITIKDGGGLAGVNNLLVRSNTRQIRLRDIQSSSYRLTHPYMTVAF
IFNGNLWRVAEMRDNRDSQFVNATGAGSFQLQAGMTTFRNSGTGKITLQLPKYANDGDSI
TTYDLDKLSSVNVATLQVYPGSGHTITYDSINGVTSVASQRSGYGVFIFDQTNNRWVVYD
GDNRVRLRRISDDLNMLPNDYVFVTPIAGNPPTVRNVTLTLPQDVAEGDRVYISMYMMGK
TQNCTIKVKDGSGETIRTNKNMMQFPQRKDYPPNDWFSVDTLTFNADTDYLPYMELSYLK
ATKEWVVAQYRPIIERVDPTNRSRLGVIALATQAEVNKNLEDLPSDELAVTPRTLANKTA
TETRRGIARLATTAEVNQNTTATFLDDVIVTPKKLNERTATEDRRGVLEIATQAETNAGT
DDTTAITPKKLDTRRASETLAGIGKLVTTGATTAEGALRGDAGTNVYNFNNGVDLITPKS
LNEKTATEKSKGLVVLATENEVITGAAAGSATMPIVVTPEMLHRKTATETRIGLIEIATQ
AETNTGTDDLRAVTPKKLNDRKATEALDGIIALASTSEIAAGTVTNKAVVPVKLKEFFDV
TGHIAVATDDGLTQSGTIWTTVNLGIASATETQRGTLRVATQGETDAGTLDTVFITPKKL
QAKKATDTAEGIIRCATNAEAGAGTATNLAITPATMQFLNGTDPAWGATTLRRGAVFITT
KSNTFIGDNLVGSTQPVDSYLEDFYAVSPRGLNFALQNFLPKMATAQNSLSLGGVVAASW
MRRDADQTVTGNNTFNGTSNFVGNVTTNGTLTANAAVTVNNTVTTNNNINQSAKANTVYA
NTVLSTATAGTKNLLRTFRGGVTDTTWHETVQASVYRLATGTTDLVDVLTVGDISNGALA
YYGTNIRLNGKALANINTAGDLFVASDATPTVQLRTAATNGWNGVTISNDNGTTTATVIN
TRNFTQHLDSTYVNTAGDTMTGALSVSVNGTGGRFTSVSGTAHVQAGDFSGNVQKMRLTG
IDDKVLTEFNINITDYNKAMINGNLIYHAGRKPTPAEIGAVAVAGSTVDTLVVRDYIKIG
NVKIFANPTTKTCEFVWEE
>35_RB16 Tail fiber hinge, essential
MANNEFMALFGPDSFTANVFSEANAVKYRLVVRGTNNDSAVNSVEVSINGADIINRRTQA
ARGINLAVIDGTTLALLDYKAFDMYGDPATNGNAIKDYLNSLPANRIVCFYTFDAIKSDD
DFLATMRKIGSVAWPETRFFNIPITTTNYSHRSSYSAIYSSTMKKICMENFVGGAGSLKD
NTTSFVEVVFDEFSDIGVTGIPERMVDDVQTYQTYQNSGDLYGFHSYGTWIVGSDVFLGD
IFKFTGELYCSQELRDAGGEVHLYMWTENSTGQWITSTILRTTGLAPDQWHSLSGYFTVP
SDPVNTKMGSQVYHYPSTVKVRLAQCRNVQITKVPREEINRNGAALGVNGVRMQTLSEVD
ASGNENPIDKLLSLPVSPTGVASDKKIISHNFAELDYIVSDPVEYTSTNTAEYQFKEWTA
TQQAAVTKASLSSYGLKAGDTIRMQCQMKRDVNAITNGKSAYIIIQFWDANNTYISGINM
RDVGTIPNVYSFYKNEGVIPAGAVTFDFGLYRYPNNTNIGTVSAKDVKLSIVR
>36_RB16 Small distal tail fiber sub, essential
MADLKLGTTLGGAGIWSASNLPLLPSGDRLTYKGWRVYTENDRPTAEDINALSTINGGTV
AKNTTFNQSVTVGINLTANTLYSKSYVDITTGGAAPGILFKRSDVTGTPSTEQGIMQITG
VNASGVALATLNINARADGGNRIYLNAYKNGTTNTSFVVDSANQQVSVELGSFRVAGSST
FAAVSATTLNVSGAITANTVTPTDWTNHDNRYITGIPRSMQGNSFGAAVVTEKNDVLSVG
GNVIDGPYGNTTYSGQVSTYRRTLNSGVSLVQTYYDTNSSWIRSGSGSPGAWSWSAGDAN
GWRRIYDTATPPTPAEVGAVNKAGDTMSGVLTLAPISQPLKTQGGGVFANDGNVYINKGG
FAGWIDDLFFKNTGGVVTGTINQDGLNSNVYCTSALSITATGSKNYLRRFRGGNGDQIWH
ETVQGGTYRLATGDTDSANLLTIESSGNMILNGSQGGSSTLFLDADSNSVVWYRMINGTE
KAVTFASNDGVYHIRTNNVRSNTWDFRAGMILNLGICSGSDYALIRGTPDGGGLDQWRER
SSGLQIDMPNGSTSAYNIWKATVWDATHVAAMDVHIPNNDGAQARVRLIHQSGAYYHFDG
SGQFTASGNGNFNDVYIRSDERLKSNLSKIESALDKVDLLEGVIYDKADHVGGEPTSREA
GLIAQQLREVLPEAVKTGEDTERNEILTVSPTAVIALLVNAIKELREEIRELKSR
>37_RB16 Large distal tail fiber sub, essential
MADLKAGTTIGGNTIWSQANLPLLPTGNTLTYKGFKVYTENDKPTKAEIGLGNVTNDAQV
KKSGDDMTGDLTLKNNTQLTVPRRINLVADTAAVAPVLLVTRSDNNAITDPFPSSETRVY
TFLANTTSNTSDPSAGAILTAHVVNQKPSGAGAMEFQVYAAPNKTTGASGRLTSKFRMSG
DDGAVSLTGSSFTVGMTTTINYNLYANELISKGAGNRNVTMQDTNGNELAMLFADTGKNL
YVRTGGSYVSRFAADGTLILANGLTVPRQVFVNGASLPVNNGQVRLDTSADGNAVGDGAT
HLGMKLEDGKYYHYFRGAGVMYIDMKGGISSSTPLYMNGVDQAIPKVEMLSTGAAGAKNF
LRRFRGGLVDTIWHETVQGGDYRLATGDTDADYQLRITADGANRGGYVFGGTFTADRGND
GFKIRYKPDTESAMFQIWNRDTSVLNSYFGYGSSNQATVSLYNRLGDIGVSTPNAAFRLD
NTTLTLGNSSSAEASQRAFTIRNWGDGEFRAAVFEVNDGTGYHFYSQRRSDNVVEAAFSG
DLYTNGTLRAQNNIIVRGSNGLEIRSDGTRHVWFKDNAGTEKAVLYAENNGSVNLRTSNQ
QYSLAIADGMIRATGQPTTGDSRGLIRGAVTGGAFAAWRDRPAGLLLDCPDSYNQAYNIW
KATHWGVAHLASMDVHNGSNSPMVLMHVGGGEFNFTAAGTLTVTGGIYASVNGDFNDVYI
RSDIRLKSNLVELKDALSKVEQLKGYIYDKKLNVEDEEPQHREAGIIAQDLQKVLPEAVK
ENEDTGMLTISPSGVNALLVNAINELRERLEAIERKIGA
>38_RB16 Sim to RB69, T2 gp38 Assem cat of distal tail fiber, essential
MAIVGVPGWIGSSAVAETGQRWMSAAGSAVRIGAPFWMSQMAGQSVYNIYIPIYDRYYNG
IRYRGCWGTGWNFPYSKPGWNATPGGSFNGLAYGTCVAVQNYLDGEYSVLTIQNGPAANF
RLTTDDGAVFNFVDTGRYDSGYRNYKIDPTQHFVWFNYLNARVGQIRQGLVAIR
>t_RB16 Holin, inner memb. pore pro., lysis timing and inhib
MALLQDKLAVLERVISFIMAVKTWKQLFIKLVLIVTIFIMFVTWYKWDDLFAVWKSSSVI
DVPTMEVEKAKKFESASIEQLNIVHLTTGADFSAVFGFRPKNVNYFVDIIAYEGKLPHQI
NPKNLGGYPIDKTSEEYNRHINGLYYVSHVASPYIPTKDLVPVAYTFSCPYFNLENYYSG
SILMEWYKQKPEVTDMKLMIVCNQAARILGRIR
>RB16ORF284c hypothetical protein
MTHEEAMKAATRGFKVSPVGKAGFFVYYNAEAGFRRITIGNVGYWNDEYVPTPYELMRVW
EIYDKSPMTKIKNFISRALSKKLKLSSNPA
>RB16ORF285c hypothetical protein
MTYEEMLNVVCAGKTAYRPTVPDMIVFREGDTIIRRSHRKVEINQVFIASVEEQKATDWD
IVAEQDHHDGLHCLHFIEMEAYGVRFHINQWCGDA
>RB16ORF286c hypothetical protein
MTNLTKVTATYFISSGAKNAMYTLRVERRGGEFTSDNYICNLSTDPDKAEAKAREYFDRM
VDRLNQTDTFQMVFQGFADFDLFERRGKLSVQDTENLELLEQGIMPIGKRKGEVIADMPM
YTILWWADQCKENGNDSPVFQAICSYCMGVALDKDYIAKREEIRAEWEAERQAKIAAAQH
IGEIGKRMEMSGVVEKVISLGYTQVSYYTEVERFMTKINVGGNVVIYYGNKIVEEGDMIK
FKATPKLHNEYKEVKQTIVQRVKVLE
>RB16ORF287c hypothetical protein
MKTALIILEEIPKNTGLYLVEADEDIIEILKTAHGHYVNGCNNTPEQDHAVNIVNLMLGP
RTDDNLAWASESNVPHEYVGMYYQCNVDDKAPLIPEKQIDLVVRTGFFL
>RB16ORF288c hypothetical protein
MNNLVAKHDFNRASTHRDRKRALKEAKRKQKHKGKCDENRFDYS
>RB16ORF289c hypothetical protein
MFIISSYYDSRQRVSLSSISKAPKDIDDFGLLNFVKKEIDRVVPEKYRIVKGSDSLTIVK
LYGEVSIQHHVPLYPR
>RB16ORF290c hypothetical protein
MKLNPFSSKIRSVDEIVATFDKTLTELEARIQHDNDQVAQVAADRKAAEEEHQRRLAELA
TKESDHTESATRAGRIADKIRKLLD
>ndd_RB16 disrupts host nucleoid; binds host HU
MTKRILTRLDIHKYAVKIGDMKRGEFTKFEGVDLKEHGFYLVVDDKTGKVVFRFYVAPNQ
RRKTGANRTLLRIKRREHEPSAMVALLDSASLYFVAHDKIKNLFGFSNLTGTIAESAIQM
RFGDGENYTEYNRALNDLFDFEFQPY
>RB16ORF292c hypothetical protein
MKLLQGVPDYWEYIDRGKRALEDSKDLWNGGNPLAGHSEDGKQTYFKKPYGYIAVALAFN
IAYAMLVLGTVNRWVEKSLVWLGTLSIRLIRLFFGVVILLVSSPIVLVMLTVNAKTGVNT
KFGNKLVKENDEKNSDKA